GSM701410[Accession] - GEO DataSets

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Items: 3

Select item 2000283691.

Expression data from LSK mice that overpexpress Ezh2 versus LSK Control

(Submitter supplied) Ezh2 is a protein member of PRC2 and has described like a functional repressor gene. We are investigating the role of Ezh2 in hematopoietic stem cell, aging and leukemia. In the present study, we generated mouse models that allow gain-of-function of Ezh2 in the hematopoietic system. Activation of Ezh2 expression specifically in self-renewing HSCs alters gene expression programs and severely compromises hematopoietic function, leading to the development of myeloproliferative disease.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL10787
6 Samples

Download data: TXT

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Accession:: GSE28369

ID:: 200028369

Select item 1000107872.

Agilent-028005 SurePrint G3 Mouse GE 8x60K Microarray (Probe Name version)

(Submitter supplied) SurePrint G3 Mouse GE 8x60K Microarray Glass slide formatted with eight high-definition 60K arrays Includes probes for mRNAs and lincRNAs (long intergenic non-coding RNAs) 60-mer oligo probes *** The ID column includes the Agilent Probe Names. A different version of this platform with the Agilent Feature Extraction feature numbers in the ID column is assigned accession number GPL13912. Protocol: see manufacturer's web site www.chem.agilent.com