GSM80548[Accession] - GEO DataSets

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Items: 4

Select item 2000035301.

Distinct Gene Expression Profiles in Adult Mouse Heart Following Targeted MAP Kinase Activation

(Submitter supplied) Three major MAP kinase signaling cascades, ERK, p38 and JNK, play significant roles in the development of cardiac hypertrophy and heart failure in response to external stress and neural/hormonal stimuli. In order to study the specific function of each MAP kinase branch in adult heart, we have generated three transgenic mouse models with cardiac specific and temporally regulated expression of activated mutants of Ras, MKK3 and MKK7, which are selective upstream activators for ERK, p38 and JNK, respectively. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS1306
Platform:: GPL1261
36 Samples

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Series

Accession:: GSE3530

ID:: 200003530

Select item 13062.

MAP kinase activation effect on heart: time course

Analysis of adult hearts after induction of activated transgene mutants of Ras, MKK3, or MKK7, which are specific upstream activators of the MAP kinases ERK, p38, and JNK respectively. Hearts examined at various time points up to 4 weeks following each transgene induction using tamoxifen.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 gender, 4 genotype/variation, 3 time sets

Platform:: GPL1261
Series:: GSE3530
36 Samples

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DataSet

Accession:: GDS1306

ID:: 1306

Select item 1000012613.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...