GEO DataSets

(Submitter supplied) Normal bladder epithelial cell explants from 2 different normal controls were treated with APF from 2 different IC patients or mock APF from 2 different matched controls. Keywords: other

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL262

8 Samples

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(Submitter supplied) Changes in human bladder epithelial cell gene expression associated with interstitial cystitis or antiproliferative factor treatment. Explanted bladder epithelial cells from patients with interstitial cystitis (IC) have been shown to differ from explanted control cells in several ways, including production of an antiproliferative factor (APF), altered production of certain epithelial growth factors, and rate of proliferation. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL262

28 Samples

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(Submitter supplied) Cells from 6 different IC patients were run in parallel with cells from their 6 different matched controls. Keywords: other

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL262

12 Samples

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(Submitter supplied) Normal bladder epithelial cell explant from a single normal control was treated with APF from a single IC patient or mock APF. Two different membranes were used. Keywords: other

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL262

8 Samples

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(Submitter supplied) Purpose: Evaluate gene expression profiles after inducing differentiation in cultured interstitial cystitis (IC) and control urothelial cells. Materials and Methods: Bladder biopsies were taken from IC patients and controls (women having surgery for stress incontinence). Primary cultures were grown in Keratinocyte Growth Medium with supplements. To induce differentiation, in some plates the medium was changed to DMEM-F12 with supplements. more...

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing

Platform:

GPL570

12 Samples

Download data: CEL, PDF

(Submitter supplied) Prolonged use of glucocorticoids can lead to the formation of a cataract, however the mechanism is not known. We recently reported the presence of the functional glucocorticoid receptor in immortalized cultured mammalian lens epithelial cells (Gupta & Wagner, Invest Ophthalmol Vis Sci 2003), but the short term biological effect of glucocorticoid action in lens epithelial cells is not known. This study seeks to examine glucocorticoid induced changes in global gene expression in LECs. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS1353

Platform:

GPL96

12 Samples

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Analysis of cultured immortalized lens epithelial cells (LEC) 4 and 16 hours after treatment with 1 uM dexamethasone, a glucocorticoid steroid hormone. Long-term glucocorticoid use can induce cataract formation. Results identify glucocorticoid targets and short-term effects of glucocorticoid on LECs

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 agent, 2 time sets

Platform:

GPL96

Series:

GSE3040

12 Samples

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(Submitter supplied) Timecourse of cAMP-induced decidualization of endometrial stromal cells. Keywords: time-course

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL8300

12 Samples

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(Submitter supplied) Interstitial cystitis (IC), a chronic bladder disease with an increasing incidence, is diagnosed using subjective symptoms in combination with cystoscopic and histological evidence. The ultimate goal is the development of a diagnostic assay for IC on a molecular level. By cystoscopic examination, IC can be classified into an ulcerative and a non-ulcerative subtype. To better understand this debilitating disease on a molecular level, a comparative gene expression profile of bladder biopsies from patients with ulcerative IC and control patients has been performed. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

16 Samples

Download data: CEL, CHP

(Submitter supplied) Human bronchial epithelial cells were treated with vehicle (control), VOSO4 (V, 50 uM) or ZnSO4 (Zn, 50 uM) for 4 hours. Keywords: other

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS1447

Platform:

GPL96

12 Samples

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Analysis of bronchial epithelial cells after 4 hours of exposure to 50 uM vanadium (V) or zinc (Zn). Excessive V and Zn in the air can arise from the burning of heavy fuel and during welding and smelting operations, respectively. Results identify biomarkers that distinguish V from Zn exposure.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 3 agent sets

Platform:

GPL96

Series:

GSE2111

12 Samples

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