GEO DataSets

(Submitter supplied) The Crabtree effect, in which fermentative metabolism is preferred at the expense of respiration, is a hallmark of budding yeast’s glucose response and a model for the Warburg effect in human tumors. While the glucose-responsive transcriptional repressors Mig1p and Mig2p play well-characterized roles in the Crabtree effect, little function for the related Mig3p transcription factor has been uncovered despite numerous investigations of laboratory yeast strains. more...

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array

Platform:

GPL13254

19 Samples

Download data: FTR, TXT

(Submitter supplied) Background We previously described the first respiratory Saccharomyces cerevisiae strain, KOY.TM6*P, by integrating the gene encoding a chimeric hexose transporter, Tm6*, into the genome of an hxt null yeast. Subsequently we demonstrated the transferability of this respiratory phenotype in the presence of up to 100 g/L glucose to a yeast strain in which only HXT1-7 had been deleted. In this study, we wanted to examine the basis of the respiratory phenotype of the resultant strain, V5.TM6*P, by comparing its transcriptome with that of its parent, V5, at different glucose concentrations. more...

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array

Platform:

GPL4423

24 Samples

Download data: TXT

(Submitter supplied) The transcription factor Cst6p in Saccharomyces cerevisiae has been reported to play important roles in several biological processes. However, the genome-wide targets of Cst6p and the mechanisms for its physiological functions remain unknown. Here, we mapped the genome-wide binding sites of Cst6p with ChIP-exo at high resolution. Cst6p binds to the promoter regions of 59 genes with various biological functions when cells are grown on ethanol, but hardly binds to the genome on glucose. more...

Organism:

Saccharomyces cerevisiae

Type:

Genome binding/occupancy profiling by high throughput sequencing

Platform:

GPL19756

4 Samples

Download data: XLSX

(Submitter supplied) Transcriptional profiling of yeast Saccharomyces serevisiae cells exposed to stress (30 min) compared to no stress conditions (YPD) in a hot1delta mutant Two stress condition experiments, YP20 and YPS, each one compared to no-stress conditions (YPD) in a hot1delta mutant

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array

Platform:

GPL9825

4 Samples

Download data: TXT

(Submitter supplied) Transcriptional profiling of yeast Saccharomyces serevisiae cells exposed to stress (30 min) compared to no stress conditions (YPD) Two stress condition experiments, YP20 and YPS, each one compared to no-stress conditions (YPD).

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array

Platform:

GPL9825

4 Samples

Download data: TXT

(Submitter supplied) Transcriptional profiles of S. cerevisiae strains with deletions of mth1, std1, or both were compared to that of a wild-type strain during growth on synthetic complete media with galactose as the carbon source, with the intent to understand each protein's contribution to the cells' response to glucose.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array

Platform:

GPL7882

6 Samples

Download data: TXT

(Submitter supplied) Caloric restriction (CR) is the only non-genetic intervention to retard aging and increase longevity in a variety of species. It is important to understand the fundamental mechanism by which CR extends lifespan that remains elusive. Owing to well-established genomic tools and convenience of culture system, we used a single cell organism, Saccharomyces cerevisiae, to clarify the mechanisms of CR. In order to identify genes responsible for CR-mediated longevity, we performed microarray experiments across the longevity assurance time-points.

Organism:

Schizosaccharomyces pombe; Saccharomyces cerevisiae BY4741; Saccharomyces cerevisiae

Type:

Expression profiling by array

Platform:

GPL2529

24 Samples

Download data: CEL, CHP

(Submitter supplied) Rsf1p is a putative transcription factor required for efficient growth using glycerol as sole carbon source but not for growth on the alternative respiratory carbon source ethanol. We use microarrays to determine the differences in the transcriptional program between the Δrsf1 mutant and the wild type during respiratory growth on glycerol as well as the transition to growth on glycerol as sole carbon source. more...

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array

Platform:

GPL90

22 Samples

Download data: CEL, CHP

(Submitter supplied) Two time courses after pulses of 0.2 g/l and 2 g/l glucose on cells growing in chemostat with galactose as the carbon source. The reference is sample from the chemostat at time 0. Groups of assays that are related as part of a time series. Keywords: time_series_design

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array

Dataset:

GDS1752

Platform:

GPL3415

26 Samples

Download data

Analysis of steady state cultures growing on galactose following a pulse of 0.2 or 2 grams of glucose per liter. Gene expression examined at various time points up to 4 hours after glucose addition. Results provide insight into the dynamics of the transcriptional response to changing environments.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array, log2 ratio, 2 dose, 18 time sets

Platform:

GPL3415

Series:

GSE4158

26 Samples

Download data

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by high throughput sequencing; Other

Platforms:

GPL17342 GPL21656

59 Samples

Download data

(Submitter supplied) Free-living cells live in fluctuating environments and must be able to respond rapidly in order to survive. Genetic background can influence how an individual responds to a changing environment, including stressful changes. Changes in gene copy number can influence stress tolerance and responses, presumably due to corresponding changes in gene expression. However, we recently showed that strains vary in their ability to tolerate gene copy number differences; how this influences variation in stress tolerance is relatively unknown. more...

Organism:

Saccharomyces cerevisiae

Type:

Other

Platform:

GPL21656

24 Samples

Download data: TXT

(Submitter supplied) We used RNA-Seq to measure transcript abundance in 4 Saccharomyces cerevisiae strains (BY4743, BC187, NCYC3290, and YPS128) from a diverse range of genetic lineages when growing in rich media (YPD) with 0.7M NaCl to characterize differential expression across strains in response to osmotic and ionic stress.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by high throughput sequencing

Platform:

GPL17342

35 Samples

Download data: TXT