GEO DataSets

(Submitter supplied) In order to explore the relative importance of adult zebrafish innate and adaptive immune responses to different kinds of infections, we compared the gene expression profile of VHSV-challenge-survivors, bacterial infection survivors and control non infected zebrafish.

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL17670

16 Samples

Download data: TXT

(Submitter supplied) We describe here the transcripts induced after infection of zebrafish with viral haemorrhagic septicemia rhabdovirus (VHSV). Two days after infection, differentially expressed transcript levels from selected immune-related zebrafish genes were studied in both fins and internal organs (pooled spleen, head kidney and liver). 

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL17670

16 Samples

Download data: TXT

(Submitter supplied) Characterization of the zebrafish embryonic host response to viral infection (CHIKV, IHNV) by means of global expression analysis

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL14629

6 Samples

Download data: TXT

(Submitter supplied) Transcriptional profiling of the zebrafish embryonic host response to a systemic bacterial infection with Salmonella typhimurium (strain SL1027); comparison between traf6 knock-down and control morpholino treated embryos.

Organism:

Danio rerio

Type:

Expression profiling by high throughput sequencing

Platform:

GPL9319

4 Samples

Download data: SAM, TXT

(Submitter supplied) Transcriptional profiling of the zebrafish embryonic host response to a systemic bacterial infection with Salmonella typhimurium (strain SL1027); comparison between traf6 knock-down and control morpholino treated embryos.

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL10042

24 Samples

Download data: TXT

(Submitter supplied) We describe for the first time transcripts induced after infection of zebrafish with VHSV. Two days after infection, differentially expressed transcript levels from selected immune-related zebrafish genes were studied using qRT-PCR in both fins and internal organs (pooled spleen, head kidney and liver).

Organism:

Danio rerio

Type:

Expression profiling by RT-PCR

Platform:

GPL9804

18 Samples

Download data: TXT

(Submitter supplied) We describe for the first time transcripts induced after infection of zebrafish with viral haemorrhagic septicemia rhabdovirus (VHSV). Two days after infection, differentially expressed transcript levels from selected immune-related zebrafish genes were studied in both fins and internal organs (pooled spleen, head kidney and liver).

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL7301

16 Samples

Download data: TXT

(Submitter supplied) Characterization of the zebrafish embryonic host response to systemic bacterial infection with Salmonella typhimurium wild type strain (SL1027) and its isogenic LPS O-antigen mutant Ra (SF1592) by means of a time-resolved global expression analysis.

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL7735

36 Samples

Download data: XML

(Submitter supplied) Gene expression profile of the response to chronic constant hypoxia in the heart of adult zebrafish Keywords: Adaptive response to chronic constant hypoxia in the heart

Organism:

Danio rerio

Type:

Expression profiling by array

Dataset:

GDS2425

Platform:

GPL1319

10 Samples

Download data: CEL, EXP

Analysis of hearts of wild type Tuebingen animals subjected to chronic constant hypoxia.

Organism:

Danio rerio

Type:

Expression profiling by array, count, 2 stress sets

Platform:

GPL1319

Series:

GSE4989

10 Samples

Download data: CEL, EXP

(Submitter supplied) We used Rag1 mutant fish vs Wild type fish to analyze the kidney transcriptomic modulation and determine how the mutation affects the general gene transcription (without stimuli) in fish, but also the immune response against Poly I:C.

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL7301

16 Samples

Download data: TXT

(Submitter supplied) Immune responses in higher vertebrates are classically separated into innate and adaptive (or specific) immunity. However, important gaps of knowledge about how adaptive responses are generated in lower vertebrates still remain unsolved. In order to explore the relative importance of adaptive and innate immune responses, we have studied zebrafish transcriptional responses to an infection with the Spring Viraemia of Carp virus (SVCV) in rag1-/- zebrafish mutants compared to wild type zebrafish by using both genome wide and immunological-targeted gene expression microarrays.

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL17670

8 Samples

Download data: TXT

(Submitter supplied) Salmonella enterica serovar Typhimurium (S. typhimurium) bacteria cause an inflammatory and lethal infection in zebrafish embryos. To characterize the embryonic innate host response at the transcriptome level, we have extended and validated previous microarray data by Illumina next-generation sequencing analysis. Comparison of tag-based sequencing (DGE or Tag-Seq) with full transcript sequencing (RNA-Seq) showed a strong correlation of sequence read counts per transcript and an overlap of 241 transcripts differentially expressed in response to infection. more...

Organism:

Danio rerio

Type:

Expression profiling by high throughput sequencing

Platform:

GPL9319

4 Samples

Download data: TXT

(Submitter supplied) We used different zebrafish transgenic lines to sort macrophages, neutrophils and immature lymphoid cells from 5-6 day old zebrafish larvae and analyzed their transcriptomes. Comparison between the different transcriptomes and gene ontology analysis revealed specificities for each cell population. Comparison with previously published data showed that zebrafish larval macrophages expressed several known human M1 and M2 macrophages. more...

Organism:

Danio rerio

Type:

Expression profiling by high throughput sequencing

Platform:

GPL14875

26 Samples

Download data: TSV, TXT

(Submitter supplied) The vertebrate kidneys play two evolutionary conserved roles in waste excretion and osmoregulation. Besides, the kidney of fish is considered as a functional ortholog of mammalian bone marrow that serves as a hematopoietic hub for generating blood cell lineages and immunological responses. However, knowledge about the properties of kidney hematopoietic cells, and the functionality of kidney in fish immune systems remain to be elucidated. more...

Organism:

Danio rerio

Type:

Expression profiling by high throughput sequencing

Platform:

GPL20828

3 Samples

Download data: MTX, TSV

(Submitter supplied) Fever implies a significant increase in corporal temperature that aids toward the resolution of infective processes such as viral disease. The majority of vertebrate species are not homeothermic therefore must rely upon the environment for temperature regulation. Here we show that in the zebrafish an artificial viral infection, induced by poly (I:C), induces a fever response regulated by the behavioral choice of temperature. more...

Organism:

Danio rerio

Type:

Expression profiling by array

Platform:

GPL6457

12 Samples

Download data: TXT