Similar studies for GEO DataSets (Select 200130582) - GEO DataSets

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Items: 20

Select item 2001305821.

Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Methylation profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platform:: GPL18573
41 Samples

Download data: COV

Series

Accession:: GSE130582

ID:: 200130582

PubMed Similar studies

Select item 2001305812.

Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function [RRBS]

(Submitter supplied) Transcriptomic and genome-wide DNA methylation was performed on T helper cells using RNA-sequencing and Reduced Representation Bisulfite Sequencing, respectively. Specific genome-wide DNA methylation analysis of T helper cells from women with PCOS identified 5,581 differentially methylated CpG sites. Interestingly, functional gene ontology enrichment analysis showed that genes located at the proximity of differentially methylated CpG sites belong to pathways related to reproductive function and immune cell function. more...

Organism:: Homo sapiens

Type:: Methylation profiling by high throughput sequencing

Platform:: GPL18573
30 Samples

Download data: COV

Series

Accession:: GSE130581

ID:: 200130581

PubMed Similar studies SRA Run Selector

Select item 2001305803.

Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function [RNAseq]

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL18573
11 Samples

Download data: TSV

Series

Accession:: GSE130580

ID:: 200130580

Select item 2001488394.

Ovarian tissue of third generation PCOS-like mice versus control animals

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing

Platform:: GPL21103
18 Samples

Download data: BW, TXT

Series

Accession:: GSE148839

ID:: 200148839

PubMed Full text in PMC Similar studies

Select item 2001488385.

Methylome profile of ovarian tissue of third generation PCOS-like mice versus control animals

(Submitter supplied) The aim of this study is to investigate possible differences in methylated regions between ovarian tissue of third generation PCOS-like (PAMH F3) mice versus control animals (CNTR)

Organism:: Mus musculus

Type:: Methylation profiling by high throughput sequencing

Platform:: GPL21103
11 Samples

Download data: BW

Series

Accession:: GSE148838

ID:: 200148838

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001474126.

Transcriptomic profile of ovarian tissue of third generation PCOS-like mice versus control animals

(Submitter supplied) The aim of this study is to investigate ovarian transcriptomic changes by RNA-seq between 2 experimental groups, control (CNTR) and the third generation of PCOS-like mice (PAMH F3).

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL21103
7 Samples

Download data: TXT

Series

Accession:: GSE147412

ID:: 200147412

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001536677.

Changes in the Epigenetic Landscape of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Reflect Systemic Dysfunctions

(Submitter supplied) Purpose: ME/CFS is a lifelong debilitating disease that affects approximately 1% of the global population. Previous studies have identified dysfunctional activity in metabolic, immune and neurological pathways. The goal of this study is to identify ME/CFS specific variations in DNA methylation to determine whether the patient specific epigenetic patterns provide insight into the disease pathophysiology. more...

Organism:: Homo sapiens

Type:: Methylation profiling by high throughput sequencing

Platform:: GPL16791
20 Samples

Download data: CSV, TXT, XLSX

Series

Accession:: GSE153667

ID:: 200153667

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2002133668.

Tissue Specific Age Acceleration in the Sperm of Oligozoospermic Men

(Submitter supplied) To determine if disease can modify aging patterns in an affected tissue without altering the aging patterns of other tissues, blood and semen of individuals with oligozoospermia (n=10) were compared to the blood and semen of individuals with normozoospermia (n=24). The Horvath and Jenkins age calculators were utilized to predict the epigenetic age of blood and sperm through the use of DNA methylation. more...

Organism:: Homo sapiens

Type:: Methylation profiling by array

Platform:: GPL21145
71 Samples

Download data: CSV, IDAT

Series

Accession:: GSE213366

ID:: 200213366

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Select item 2000804689.

DNA methylation profiling of polycystic ovarian syndrome (PCOS)

(Submitter supplied) Genome-wide DNA methylation analysis on PCOS using Illumina HumanMethylation 450K BeadChips in 30 PCOS patients and 30 healthy controls

Organism:: Homo sapiens

Type:: Methylation profiling by genome tiling array

Platform:: GPL13534
60 Samples

Download data: IDAT

Series

Accession:: GSE80468

ID:: 200080468

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20009326610.

DNA methylome modifications in ME/CFS

(Submitter supplied) Examination of DNA methylome patterns in a larger cohort of ME/CFS samples using the Illumina Infinium HumanMethylation450 Beadchip Array

Organism:: Homo sapiens

Type:: Methylation profiling by genome tiling array

Platform:: GPL13534
75 Samples

Download data: IDAT, TXT

Series

Accession:: GSE93266

ID:: 200093266

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20010229311.

Enhanced Inflammatory Transcriptome in the Granulosa Cells of Women With Polycystic Ovarian Syndrome

(Submitter supplied) Context: Polycystic ovarian syndrome (PCOS), the most common endocrine disorder of reproductive- aged women, is associated with systemic low-grade inflammation. Objective: We propose that increased or altered intrafollicular inflammatory reactions also occur in periovulatory follicles of PCOS patients. Design: Gene profiling and quantitative PCR (qPCR) analyses in granulosa-lutein cells (GCs) collected from PCOS and non-PCOS women undergoing in vitro fertilization were compared with serum and follicular fluid (FF) levels of cytokines and chemokines. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
6 Samples

Download data: CEL

Series

Accession:: GSE102293

ID:: 200102293

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20013859812.

Whole genome bisulfite sequencing of human spermatozoa reveals differentially methylated patterns from type 2 diabetic patients

(Submitter supplied) We investigated the genome-wide DNA methylation profiles in sperm by comparing 8 individuals with T2DM and 9 non-diabetic controls using whole genome bisulfite sequencing (WGBS) method. Our study provides the first evidence that T2DM reprograms sperm DNA methylome and provides new insights into the intricate mechanisms of susceptibility to T2DM in offspring.

Organism:: Homo sapiens

Type:: Methylation profiling by high throughput sequencing

Platform:: GPL16791
17 Samples

Download data: TXT

Series

Accession:: GSE138598

ID:: 200138598

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Select item 20014284413.

DNA methylation and gene expression signatures are associated with ataxia-telangiectasia phenotype

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing

Platform:: GPL18573
24 Samples

Download data: COV

Series

Accession:: GSE142844

ID:: 200142844

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Select item 20014284314.

DNA methylation and gene expression signatures are associated with ataxia-telangiectasia phenotype [DNA methylation/RRBS]

(Submitter supplied) People with ataxia-telangiectasia (A-T) display clinical variability, yet molecular profiles associated with distinct A-T phenotypes remain undefined. We report transcriptional and DNA methylation signatures that inform the regulatory networks underlying A-T phenotypes.

Organism:: Homo sapiens

Type:: Methylation profiling by high throughput sequencing

Platform:: GPL18573
12 Samples

Download data: COV

Series

Accession:: GSE142843

ID:: 200142843

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Select item 20014284215.

DNA methylation and gene expression signatures are associated with ataxia-telangiectasia phenotype [gene expression/RNA-seq]

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL18573
12 Samples

Download data: TXT

Series

Accession:: GSE142842

ID:: 200142842

PubMed Full text in PMC Similar studies

Select item 20007639916.

The epigenetic signature of systemic insulin resistance in obese women

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Methylation profiling by genome tiling array

Platform:: GPL13534
236 Samples

Download data

Series

Accession:: GSE76399

ID:: 200076399

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20007639817.

The epigenetic signature of systemic insulin resistance in obese women [SC]

(Submitter supplied) Impaired ability of insulin to stimulate cellular glucose uptake and regulate metabolism, that is insulin resistance (IR), links adiposity to metabolic disorders such as type 2 diabetes (T2D), dyslipidemia and cardiovascular disease (Langenberg, 2012). Both genetic and epigenetic factors are implicated in development of systemic IR (Vaag, 2001). IR is characterized by elevated levels of fasting insulin in the general circulation. more...