Similar studies for GEO DataSets (Select 200220928) - GEO DataSets

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Items: 20

Select item 2002209281.

Skeletal muscle DNA methylation and mRNA responses to a bout of higher versus lower load resistance exercise in previ-ously trained men

(Submitter supplied) We sought to determine the skeletal muscle genome-wide DNA methylation and mRNA respons-es to one bout of lower-load (LL) versus higher-load (HL) resistance exercise. Trained col-lege-aged males (n=11, 23±4 years old, 4±3 years self-reported training) performed LL or HL bouts to failure separated by one week. The HL bout (i.e., 80 Fail) consisted of four sets of back squats and four sets of leg extensions to failure using 80% of participants estimated one-repetition maximum (i.e., est. more...

Organism:: Homo sapiens

Type:: Methylation profiling by genome tiling array

Platform:: GPL21145
64 Samples

Download data: CSV, IDAT, PDF

Series

Accession:: GSE220928

ID:: 200220928

PubMed Full text in PMC Similar studies

Select item 2002208992.

Genome-wide DNA methylation and mRNA responses to a bout of higher versus lower load resistance training in previously trained men

(Submitter supplied) We sought to determine skeletal muscle genome-wide DNA methylation and transcriptome changes to one bout of lower-load (LL) versus higher-load (HL) resistance exercise. Previously trained college-aged males (n=11, age: 23±4 years old, training experience: 4 ± 3 years) performed LL or HL bouts to failure separated by one week. The HL bout (a.k.a., 80 Fail) consisted of four sets of back squats and four sets of leg extensions to failure using 80% of their estimated one-repetition maximum (i.e., est. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL24324
64 Samples

Download data: CEL

Series

Accession:: GSE220899

ID:: 200220899

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001147633.

Human Muscle Posses Epigenetic Memory

(Submitter supplied) It is unknown if adult human skeletal muscle has an epigenetic memory of earlier encounters with growth. We report, for the first time in humans, genome-wide DNA methylation (850,000CpGs) and gene expression analysis after muscle hypertrophy (loading), return of muscle mass to baseline (unloading), followed by later hypertrophy (reloading). We discovered increased frequency of hypomethylation across the genome after reloading (18,816 CpGs) versus earlier loading (9,153 CpG sites). more...

Organism:: Homo sapiens

Type:: Methylation profiling by genome tiling array

Platform:: GPL21145
40 Samples

Download data: IDAT

Series

Accession:: GSE114763

ID:: 200114763

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Select item 2000582804.

Multi-Omic Integrated networks connect DNA methylation and miRNA with skeletal muscle plasticity to chronic exercise in type 2 diabetic obesity [Methylation data]

(Submitter supplied) Analysis of skeletal muscle DNA methylation from type 2 diabetic volunteers before and after 16 weeks of chronic exercise training (two groups, one undergoing aerobic excercise and the other resistance training exercise)

Organism:: Homo sapiens

Type:: Methylation profiling by array

Platform:: GPL13534
34 Samples

Download data: TXT

Series

Accession:: GSE58280

ID:: 200058280

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Select item 2000582505.

Multi-Omic Integrated networks connect DNA methylation and miRNA with skeletal muscle plasticity to chronic exercise in type 2 diabetic obesity

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: synthetic construct; Homo sapiens

Type:: Non-coding RNA profiling by array; Expression profiling by array; Methylation profiling by array

Platforms:: GPL13534 GPL14613 GPL10558
102 Samples

Download data: CEL, CHP

Series

Accession:: GSE58250

ID:: 200058250

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000582496.

Multi-Omic Integrated networks connect DNA methylation and miRNA with skeletal muscle plasticity to chronic exercise in type 2 diabetic obesity [mRNA data]

(Submitter supplied) Analysis of skeletal muscle gene expression from type 2 diabetic volunteers before and after 16 weeks of chronic exercise training (two groups, one undergoing aerobic ecercise and the other resistance training exercise)

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
34 Samples

Download data: TXT

Series

Accession:: GSE58249

ID:: 200058249

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000582487.

Multi-Omic Integrated networks connect DNA methylation and miRNA with skeletal muscle plasticity to chronic exercise in type 2 diabetic obesity [miRNA data]

(Submitter supplied) Analysis of skeletal muscle miRNA expression from type 2 diabetic volunteers before and after 16 weeks of chronic exercise training (two groups, one undergoing aerobic ecercise and the other resistance training exercise)

Organism:: synthetic construct; Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL14613
34 Samples

Download data: CEL, CHP

Series

Accession:: GSE58248

ID:: 200058248

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001079348.

Transcriptome response of human skeletal muscle to divergent exercise stimuli

(Submitter supplied) While acute aerobic and resistance exercise stimulate a number of shared genes, each exercsie mode stimlutes a number of uniquely responsive genes, thus highlighting that different forms of exercise facilitate distinct molecular responses in skeletal muscle.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL16791
29 Samples

Download data: TXT

Series

Accession:: GSE107934

ID:: 200107934

Select item 2002130299.

Aerobic Exercise Training Rejuvenates the Human Skeletal Muscle Methylome Ten years after Breast Cancer Treatment and Survival

(Submitter supplied) Many cancer survivors suffer from impairments in skeletal muscle (SkM), both in terms of reduced mass and function. Interestingly, human SkM possesses an epigenetic memory of earlier stimuli, such as exercise. Long-term retention of epigenetic changes in SkM following cancer survival and/or exercise training have not yet been studied. We therefore investigated genome-wide DNA methylation (the methylome) in SkM following a 5-month, 3/week treadmill-based aerobic training intervention in breast cancer survivors 10-14 years after diagnosis and treatment. more...

Organism:: Homo sapiens

Type:: Methylation profiling by array

Platform:: GPL21145
32 Samples

Download data: IDAT, TXT

Series

Accession:: GSE213029

ID:: 200213029

Select item 20004542610.

Transcriptional events in human skeletal muscle at the outset of concentric resistance exercise training

(Submitter supplied) We sought to ascertain the time-course of transcriptional events that occur in human skeletal muscle at the outset of resistance exercise (RE) training in RE naïve individuals, and determine if the magnitude of any response was associated with exercise induced muscle damage. Sixteen RE naïve males were recruited, 8 underwent 2 sessions of 5x30 maximum, isokinetic knee extensions (180°.s-1) separated by 48 hrs. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4820
Platform:: GPL570
45 Samples

Download data: CEL

Series

Accession:: GSE45426

ID:: 200045426

Select item 482011.

Skeletal muscle initial response to concentric resistance exercise training: time course

Analysis of vastus lateralis biopsies taken at the outset (day 1, 2 and 4) of concentric resistance exercise (RE) training in RE naive individuals. Results provide insight into molecular mechanisms underlying the initial transient response of skeletal muscle to concentric RE.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 protocol, 3 time sets

Platform:: GPL570
Series:: GSE45426
45 Samples

Download data: CEL

DataSet

Accession:: GDS4820

ID:: 4820

Select item 20016228812.

The comparative methylome and transcriptome after change of direction compared to straight line running exercise in human skeletal muscle

(Submitter supplied) The methylome and transcriptome signatures following exercise that are physiologically and metabolically relevant to sporting contexts such as team sports or health prescription scenarios (e.g. high intensity interval training/HIIT) has not been investigated. To explore this, we performed two different sport/exercise relevant high-intensity running protocols in 5 male sport team members using a repeated measures design of: 1) Change of direction (COD) versus; 2) straight line (ST) exercise with a wash-out period of at least 2 weeks between trials. more...

Organism:: Homo sapiens

Type:: Methylation profiling by array

Platform:: GPL21145
16 Samples

Download data: TXT

Series

Accession:: GSE162288

ID:: 200162288

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20007419413.

Muscle Transcriptome Profile of Resistance Exercise is Augmented by Aerobic Exercise

(Submitter supplied) 10 male subjects performed ~45 min one-legged cycling and 4 x 7 maximal concentric-eccentric knee extensions for each leg 15 min later. Thus, one limb performed aerobic and resistance exercise (AE+RE), while the opposing leg did resistance exercise only (RE). Biopsies were obtained from m. vastus lateralis of each leg 3 h after the resistance exercise bout. Gene expression analysis was carried out on the Affymetrix HuGene-2.1-st platform.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL17692
20 Samples

Download data: CEL

Series

Accession:: GSE74194

ID:: 200074194

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20015106614.

Skeletal muscle transcriptome response to a bout of endurance exercise in physically active and sedentary older adults

(Submitter supplied) Age-related declines in cardiorespiratory fitness and physical function are mitigated by regular endurance exercise in older adults. This may be due, in part, to changes in the transcriptional program of skeletal muscle following repeated bouts of exercise. However, the impact of chronic exercise training on the transcriptional response to an acute bout of endurance exercise has not been clearly determined. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24676
57 Samples

Download data: TXT

Series

Accession:: GSE151066

ID:: 200151066

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 20000424715.

cDNA microarray analysis of human skeletal muscle after endurance exercise

(Submitter supplied) We examined global mRNA expression using cDNA microarrays in skeletal muscle of humans before, and 3h and 48h after a single bout of exhaustive endurance exercise (cycling). Keywords: Time course

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS1679
Platform:: GPL3457
8 Samples

Download data: GPR

Series

Accession:: GSE4247

ID:: 200004247

Select item 10000345716.

Buck Institute Human 8k cDNA microarray

(Submitter supplied) 8,432 randomly chosen cDNAs from a 40k Research Genetics human cDNA library were amplified under standard conditions (GeneAmp PCR System 9700) with the help of a volumetric robot (Tecan/Genesis, RSP150 and Tomtec/Quadra 384). Amplified products were transferred to a 384-well plates, purified transferred to 384-well print plates (Genetix), dried and resuspended in print buffer (3xSSC, 1.5M Betaine). more...

Organism:: Homo sapiens

2 DataSets
3 Series
15 Samples

Download data

Platform

Accession:: GPL3457

ID:: 100003457

PubMed Similar studies

Select item 167917.

Exhaustive endurance exercise effect on skeletal muscle: time course

Expression profiling of vastus lateralis muscles 3 and 48 hours after a 75-minute bout of high-intensity cycling. Results identify transcriptional pathways activated in skeletal muscles recovering from endurance exercise.