GEO DataSets

Analysis of true interval breast cancers (TIBCs; tumors appearing after a negative screening mammogram) and mammogram screen-detected breast cancers (SDBCs). The development and progression of TIBCs differ from those of SDBCs. Results provide insight into the molecular mechanisms underlying TIBCs.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 disease state, 4 genotype/variation sets

Platform:

GPL6244

Series:

GSE47108

10 Samples

Download data: CEL

(Submitter supplied) Background: Interval breast cancers can occur through failure to detect an abnormality at the time of screening (missed interval cancer), or as a new event after a negative screen (true interval cancer). The development and progression of true interval tumors (TIBC) is known to be different than screen-detected tumors (SDBC). However, much work still needs to be done to understand the biological characteristics and clinical behaviour of these TIBC. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS4760

Platform:

GPL6244

10 Samples

Download data: CEL

(Submitter supplied) To address the molecular mechanisms underlying c-Src-mediated tumor progression, we previously developed a model system using Csk-deficient fibroblasts that can be transformed by wild-type c-Src. In this study, we applied this system for the analysis of the potential contribution of miRNA to c-Src-mediated transformation. Pair-wise significance analysis of the microarray indicated that seven miR genes were significantly upregulated and six miRNA genes were downregulated in c-Src-transformed cells with a P value below 0.01 and with a fold change over 2.0.

Organism:

Mus musculus

Type:

Non-coding RNA profiling by array

Platform:

GPL9756

8 Samples

Download data: TXT