GEO DataSet Links for PMC (Select 2376757) - GEO DataSets

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Items: 2

Select item 2000088321.

K562 Gene Expression Control vs 1R-Chl treatments

(Submitter supplied) To determine whether the polyamide-Chl conjugate 1R-Chl would cause similar changes in global gene expression in K562 cells, affymetrix gene chip analysis was performed using 1R-Chl. Through class comparison analysis, 1R-Chl affected the levels of transcription and genes of interest were determined. Keywords: Treatment response

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS2970
Platform:: GPL570
6 Samples

Download data: CEL, CHP, EXP

Series

Accession:: GSE8832

ID:: 200008832

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 29702.

Polyamide-chlorambucil conjugate 1R-Chl effect on leukemia cell line

Analysis of leukemia K562 cells treated with the polyamide-chlorambucil conjugate 1R-Chl. 1R-Chl down-regulates transcription of the human histone H4c gene and inhibits the growth of several cancer cell lines in vitro.