GEO DataSets

(Submitter supplied) Introduction: A number of genetic-association studies have identified genes contributing to AS susceptibility but such approaches provide little information as to the gene activity changes occurring during the disease process. Transcriptional profiling generates a “snapshot” of the sampled cells activity and thus can provide insights into the molecular processes driving the disease process. We undertook a whole-genome microarray approach to identify candidate genes associated with AS and validated these gene-expression changes in a larger sample cohort. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS5231

Platform:

GPL6947

32 Samples

Download data: TXT

Analysis of whole blood samples from patients with ankylosing spondylitis (AS). AS is a chronic inflammatory rheumatic disease characterized by inflammation that leads to bone resorption and bone formation. Results provide insight into the molecular pathogenesis of AS.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 disease state sets

Platform:

GPL6947

Series:

GSE25101

32 Samples

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