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Items: 2

1.

Adrenalectomy plus corticosterone treatment, rat hippocampal RNA-seq

(Submitter supplied) Male Sprague-Dawley rats 8 weeks old, were adrenalectomized, treated with 300ug/kg corticosterone or vehicle 3 days after surgery then sacrificed 1 hour later. Hippocampi were removed and RNA extracted and processed for sequencing at the Massachusetts General Hospital Nex-Generation Sequening Core.
Organism:
Rattus norvegicus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL14844
12 Samples
Download data: BED, TAB
Series
Accession:
GSE84249
ID:
200084249
2.

Two Populations of Glucocorticoid Receptor-Binding Sites in the Male Rat Hippocampal Genome

(Submitter supplied) In the present study, genomic binding sites of glucocorticoid receptors (GR) were identified in vivo in the rat hippocampus applying chromatin immunoprecipitation followed by next-generation sequencing. We identified 2470 significant GR-binding sites (GBS) and were able to confirm GR binding to a random selection of these GBS covering a wide range of P values. Analysis of the genomic distribution of the significant GBS revealed a high prevalence of intragenic GBS. more...
Organism:
Rattus norvegicus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL11282
4 Samples
Download data: BED, WIG
Series
Accession:
GSE84202
ID:
200084202

Supplemental Content

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