GEO DataSet Links for SRA (Select 6622952) - GEO DataSets

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Links from SRA

Items: 2

Select item 3034428561.

Wild type intestinal spheroid cells

Organism:: Mus musculus

Source name:: intestinal spheroid cells of wild type mice

Platform:: GPL17021
Series:: GSE121658

Download data: BED, TXT

Sample

Accession:: GSM3442856

ID:: 303442856

SRA Run Selector

Select item 2001216582.

Essential role of Arid1a in intestinal stem cell maintenance and homeostasis through Sox9 regulation (ChIP-Seq)

(Submitter supplied) Arid1a, a subunit of the SWI/SNF chromatin remodeling complex, have been reported in multiple human cancers, however, its functional role in intestinal homeostasis remains unclear. To investigate the role of Arid1a in murine intestine, we have employed ChIP experiments in intestinal spheroid cells generated from crypt cells of wild type mice. ChIP assay revealed that Arid1a binds directly to the Sox9 promoter to support its expression.