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zeb1a - zinc finger E-box binding homeobox 1a

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including regulation of cell-cell adhesion involved in gastrulation; regulation of gastrulation; and smooth muscle tissue development. Is expressed in hypoblast and neural plate. Human ortholog(s) of this gene implicated in Fuchs' endothelial dystrophy and posterior polymorphous corneal dystrophy 3. Orthologous to human ZEB1 (zinc finger E-box binding homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

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Species Gene Architecture aa