grpel2 GrpE-like 2, mitochondrial [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: grpel2provided by ZNC
Official Full Name: GrpE-like 2, mitochondrialprovided by ZNC
Primary source: ZFIN:ZDB-GENE-091204-188
See related: Ensembl:ENSDARG00000069421 AllianceGenome:ZFIN:ZDB-GENE-091204-188
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:dkey-25l11.3
Summary: Predicted to enable adenyl-nucleotide exchange factor activity and unfolded protein binding activity. Predicted to be involved in protein import into mitochondrial matrix. Predicted to act upstream of or within protein folding. Predicted to be part of PAM complex, Tim23 associated import motor. Orthologous to human GRPEL2 (GrpE like 2, mitochondrial). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 21

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	21	NC_007132.7 (30409567..30415508, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	21	NC_007132.6 (30372872..30378813, complement)

Chromosome 21 - NC_007132.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fc75e12.x1 (e-PCR)
- UniSTS:194452

fc24d06.y1 (e-PCR)
- UniSTS:193195

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables adenyl-nucleotide exchange factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables adenyl-nucleotide exchange factor activity	IEA Inferred from Electronic Annotation more info
enables protein homodimerization activity	IEA Inferred from Electronic Annotation more info
enables protein-folding chaperone binding	IEA Inferred from Electronic Annotation more info
enables unfolded protein binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within protein folding	IEA Inferred from Electronic Annotation more info
involved_in protein import into mitochondrial matrix	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of PAM complex, Tim23 associated import motor	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: grpE protein homolog 2, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001288663.1 → NP_001275592.1 grpE protein homolog 2, mitochondrial

Status: VALIDATED

Source sequence(s)

CT677933, CT677934, EB871414

UniProtKB/TrEMBL

A0A8M1P5R5, E7F0C3

Related

ENSDARP00000091810.4, ENSDART00000101036.5

Conserved Domains (1) summary

cd00446
Location:77 → 210

GrpE; nucleotide exchange factor GrpE