shld2 shieldin complex subunit 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: shld2provided by ZNC
Official Full Name: shieldin complex subunit 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-090313-30
See related: Ensembl:ENSDARG00000038686 AllianceGenome:ZFIN:ZDB-GENE-090313-30
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fam35a; si:ch211-134m17.9
Summary: Predicted to be involved in regulation of double-strand break repair via homologous recombination. Predicted to be active in nucleus and site of double-strand break. Orthologous to human SHLD2 (shieldin complex subunit 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 13

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	13	NC_007124.7 (22698215..22715102)
105	previous assembly	GRCz10 (GCF_000002035.5)	13	NC_007124.6 (22567765..22584652)

Chromosome 13 - NC_007124.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in regulation of double-strand break repair via homologous recombination	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
is_active_in site of double-strand break	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: protein FAM35A; shieldin complex subunit 2

Names: family with sequence similarity 35, member A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001145633.1 → NP_001139105.1 shieldin complex subunit 2

Status: PROVISIONAL

Source sequence(s)

BX005174

UniProtKB/TrEMBL

A0A8M1NTG0, B8A4B1

Related

ENSDARP00000117245.1, ENSDART00000137467.3

Conserved Domains (1) summary

pfam15793
Location:598 → 780

FAM35_C; Protein family FAM35, C-terminal

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007124.7 Reference GRCz11 Primary Assembly

Range

22698215..22715102

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005156727.4 → XP_005156784.1 protein FAM35A isoform X1

UniProtKB/TrEMBL

A0A8M2B2T0

Conserved Domains (1) summary

pfam15793
Location:598 → 773

FAM35_C; Protein family FAM35, C-terminal