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ajap1 adherens junctions associated protein 1 [ Danio rerio (zebrafish) ]

Gene ID: 101887016, updated on 27-Mar-2024

Summary

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Official Symbol
ajap1provided by ZNC
Official Full Name
adherens junctions associated protein 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-041210-353
See related
Ensembl:ENSDARG00000038655 AllianceGenome:ZFIN:ZDB-GENE-041210-353
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkey-11c8.1
Summary
Predicted to enable beta-catenin binding activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in adherens junction; cell-cell contact zone; and cytoplasmic side of plasma membrane. Predicted to be spanning component of plasma membrane. Orthologous to human AJAP1 (adherens junctions associated protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
6
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (21588225..21672075)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (21556124..21639982)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene transmembrane protein 26-like Neighboring gene forkhead-associated (FHA) phosphopeptide binding domain 1 Neighboring gene nephronophthisis 4 Neighboring gene nephrocystin-4-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Molecular and cellular characterization of a zebrafish optic pathway tumor line implicates glia-derived progenitors in tumorigenesis. Solin SL, et al. PLoS One, 2014. PMID 25485542, Free PMC Article
  2. Transcripts within rod photoreceptors of the Zebrafish retina. Sun C, et al. BMC Genomics, 2018 Feb 8. PMID 29422031, Free PMC Article
  3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables beta-catenin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in adherens junction IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cell-cell contact zone IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasmic side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
adherens junction-associated protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    21588225..21672075
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021478418.1 → XP_021334093.1  adherens junction-associated protein 1

    UniProtKB/TrEMBL
    A0A0R4IPJ8, A0A8M2BEF5
    Related
    ENSDARP00000138073.2, ENSDART00000172190.2
    Conserved Domains (1) summary
    pfam15298
    Location:170 → 361
    AJAP1_PANP_C; AJAP1/PANP C-terminus

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395271.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    130903..211992
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005166950.4 → XP_005167007.1  adherens junction-associated protein 1

    See identical proteins and their annotated locations for XP_005167007.1

    UniProtKB/TrEMBL
    A0A0R4IPJ8, A0A8M2BEF5
    Conserved Domains (1) summary
    pfam15298
    Location:170 → 361
    AJAP1_PANP_C; AJAP1/PANP C-terminus
Nucleotide Protein
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