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ARHGAP32 Rho GTPase activating protein 32 [ Chelonia mydas (Green sea turtle) ]

Gene ID: 102943578, updated on 10-Mar-2024

Summary

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Gene symbol
ARHGAP32
Gene description
Rho GTPase activating protein 32
Locus tag
UY3_13253
See related
EnsemblRapid:ENSCMYG00015001089
Gene type
protein coding
RefSeq status
MODEL
Organism
Chelonia mydas
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Americhelydia; Chelonioidea; Cheloniidae; Chelonia
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 22
Exon count:
26
Annotation release Status Assembly Chr Location
103 current rCheMyd1.pri.v2 (GCF_015237465.2) 22 NC_051262.2 (5887120..6153696, complement)
102 previous assembly rCheMyd1.pri (GCF_015237465.1) 20 NC_051260.1 (13102888..13369416)

Chromosome 22 - NC_051262.2Genomic Context describing neighboring genes Neighboring gene Fli-1 proto-oncogene, ETS transcription factor Neighboring gene potassium inwardly rectifying channel subfamily J member 5 Neighboring gene potassium inwardly rectifying channel subfamily J member 1 Neighboring gene uncharacterized LOC122463590 Neighboring gene uncharacterized LOC122463576

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sea turtle fibropapilloma tumors share genomic drivers and therapeutic vulnerabilities with human cancers. Duffy DJ, et al. Commun Biol, 2018. PMID 30271945, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cell cortex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in fibrillar center IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho GTPase-activating protein 32

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Chelonia mydas Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference rCheMyd1.pri.v2 Primary Assembly

Genomic

  1. NC_051262.2 Reference rCheMyd1.pri.v2 Primary Assembly

    Range
    5887120..6153696 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_037882261.2 → XP_037738189.1  rho GTPase-activating protein 32 isoform X4

    Related
    ENSCMYP00015001674.1, ENSCMYT00015002035.1
    Conserved Domains (4) summary
    cd07298
    Location:123 → 237
    PX_RICS; The phosphoinositide binding Phox Homology domain of PX-RICS
    cd11835
    Location:259 → 312
    SH3_ARHGAP32_33; Src homology 3 domain of Rho GTPase-activating proteins 32 and 33, and similar proteins
    PHA03247
    Location:1164 → 1561
    PHA03247; large tegument protein UL36; Provisional
    cd04384
    Location:364 → 558
    RhoGAP_CdGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of CdGAP-like proteins; CdGAP contains an N-terminal RhoGAP domain and a C-terminal proline-rich region, and it is active on both Cdc42 and Rac1 but not RhoA. CdGAP is recruited to ...

  2. XM_043534160.1 → XP_043390095.1  rho GTPase-activating protein 32 isoform X2

    Related
    ENSCMYP00015001675.1, ENSCMYT00015002036.1
    Conserved Domains (4) summary
    cd07298
    Location:123 → 237
    PX_RICS; The phosphoinositide binding Phox Homology domain of PX-RICS
    cd11835
    Location:259 → 312
    SH3_ARHGAP32_33; Src homology 3 domain of Rho GTPase-activating proteins 32 and 33, and similar proteins
    PHA03247
    Location:1206 → 1603
    PHA03247; large tegument protein UL36; Provisional
    cd04384
    Location:406 → 600
    RhoGAP_CdGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of CdGAP-like proteins; CdGAP contains an N-terminal RhoGAP domain and a C-terminal proline-rich region, and it is active on both Cdc42 and Rac1 but not RhoA. CdGAP is recruited to ...

  3. XM_043534161.1 → XP_043390096.1  rho GTPase-activating protein 32 isoform X3

    Related
    ENSCMYP00015001671.1, ENSCMYT00015002032.1
    Conserved Domains (4) summary
    cd07298
    Location:137 → 251
    PX_RICS; The phosphoinositide binding Phox Homology domain of PX-RICS
    cd11835
    Location:273 → 326
    SH3_ARHGAP32_33; Src homology 3 domain of Rho GTPase-activating proteins 32 and 33, and similar proteins
    PHA03247
    Location:1178 → 1575
    PHA03247; large tegument protein UL36; Provisional
    cd04384
    Location:378 → 572
    RhoGAP_CdGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of CdGAP-like proteins; CdGAP contains an N-terminal RhoGAP domain and a C-terminal proline-rich region, and it is active on both Cdc42 and Rac1 but not RhoA. CdGAP is recruited to ...

  4. XM_043534159.1 → XP_043390094.1  rho GTPase-activating protein 32 isoform X1

    Conserved Domains (4) summary
    cd07298
    Location:137 → 251
    PX_RICS; The phosphoinositide binding Phox Homology domain of PX-RICS
    cd11835
    Location:273 → 326
    SH3_ARHGAP32_33; Src homology 3 domain of Rho GTPase-activating proteins 32 and 33, and similar proteins
    PHA03247
    Location:1220 → 1617
    PHA03247; large tegument protein UL36; Provisional
    cd04384
    Location:420 → 614
    RhoGAP_CdGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of CdGAP-like proteins; CdGAP contains an N-terminal RhoGAP domain and a C-terminal proline-rich region, and it is active on both Cdc42 and Rac1 but not RhoA. CdGAP is recruited to ...

  5. XM_037882263.2 → XP_037738191.1  rho GTPase-activating protein 32 isoform X5

    UniProtKB/TrEMBL
    M7B2B6
    Conserved Domains (2) summary
    PHA03247
    Location:819 → 1216
    PHA03247; large tegument protein UL36; Provisional
    cd04384
    Location:19 → 213
    RhoGAP_CdGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of CdGAP-like proteins; CdGAP contains an N-terminal RhoGAP domain and a C-terminal proline-rich region, and it is active on both Cdc42 and Rac1 but not RhoA. CdGAP is recruited to ...
Nucleotide Protein
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