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HEY2 hes related family bHLH transcription factor with YRPW motif 2 [ Panthera leo (lion) ]

Gene ID: 122220360, updated on 22-Mar-2024

Summary

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Gene symbol
HEY2
Gene description
hes related family bHLH transcription factor with YRPW motif 2
See related
EnsemblRapid:ENSPLXG00005019043
Gene type
protein coding
RefSeq status
MODEL
Organism
Panthera leo
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Pantherinae; Panthera
Orthologs
human mouse all
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Genomic context

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See HEY2 in Genome Data Viewer
Location:
chromosome: B2
Exon count:
5
Annotation release Status Assembly Chr Location
100 current P.leo_Ple1_pat1.1 (GCF_018350215.1) B2 NC_056683.1 (112697515..112709837)

Chromosome B2 - NC_056683.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC122220359 Neighboring gene phosphatidylinositol N-acetylglucosaminyltransferase subunit P-like Neighboring gene transfer RNA glutamic acid (anticodon CUC) Neighboring gene nuclear receptor coactivator 7 Neighboring gene uncharacterized LOC122220364

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056683.1 Chromosome B2 Reference P.leo_Ple1_pat1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in anterior/posterior pattern specification IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in circulatory system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of neurogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hairy/enhancer-of-split related with YRPW motif protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Panthera leo Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference P.leo_Ple1_pat1.1 Primary Assembly

Genomic

  1. NC_056683.1 Reference P.leo_Ple1_pat1.1 Primary Assembly

    Range
    112697515..112709837
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042939752.1 → XP_042795686.1  hairy/enhancer-of-split related with YRPW motif protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C9D7T0
    Related
    ENSPLXP00005025350.1, ENSPLXT00005039285.1
    Conserved Domains (2) summary
    smart00511
    Location:119 → 165
    ORANGE; Orange domain
    cd18920
    Location:40 → 121
    bHLH-O_HEY2; basic helix-loop-helix-orange (bHLH-O) domain found in hairy/enhancer-of-split related with YRPW motif protein 2 (HEY2) and similar proteins

  2. XM_042939753.1 → XP_042795687.1  hairy/enhancer-of-split related with YRPW motif protein 2 isoform X2

    Related
    ENSPLXP00005025354.1, ENSPLXT00005039292.1
    Conserved Domains (2) summary
    smart00511
    Location:119 → 165
    ORANGE; Orange domain
    cd18920
    Location:40 → 121
    bHLH-O_HEY2; basic helix-loop-helix-orange (bHLH-O) domain found in hairy/enhancer-of-split related with YRPW motif protein 2 (HEY2) and similar proteins
Nucleotide Protein
Heading Accession and Version

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