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TCF7L2 transcription factor 7 like 2 [ Neogale vison (American mink) ]

Gene ID: 122901120, updated on 22-Mar-2024

Summary

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Gene symbol
TCF7L2
Gene description
transcription factor 7 like 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Neogale vison
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae; Mustelinae; Neogale
Also known as
Tcf-4; F8W742
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
19
Annotation release Status Assembly Chr Location
100 current ASM_NN_V1 (GCF_020171115.1) 2 NC_058092.1 (223205567..223403365)

Chromosome 2 - NC_058092.1Genomic Context describing neighboring genes Neighboring gene U4 spliceosomal RNA Neighboring gene glyceraldehyde-3-phosphate dehydrogenase-like Neighboring gene hyaluronan binding protein 2 Neighboring gene nebulin related anchoring protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_058092.1 Chromosome 2 Reference ASM_NN_V1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TGF-beta induces novel Lef-1 splice variants through a Smad-independent signaling pathway. Cordray P, et al. Dev Dyn, 2005 Apr. PMID 15736165

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of beta-catenin-TCF complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of catenin-TCF7L2 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transcription factor 7-like 2
Names
T-cell transcription factor 4
Transcription factor 7-like 2 (T-cell-specific, HMG-box)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Neovison vison Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM_NN_V1 Primary Assembly

Genomic

  1. NC_058092.1 Reference ASM_NN_V1 Primary Assembly

    Range
    223205567..223403365
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044240523.1 → XP_044096458.1  transcription factor 7-like 2 isoform X1

    Conserved Domains (2) summary
    cd01388
    Location:406 → 473
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 307
    CTNNB1_binding; N-terminal CTNNB1 binding

  2. XM_044240528.1 → XP_044096463.1  transcription factor 7-like 2 isoform X6

    Conserved Domains (2) summary
    cd01388
    Location:406 → 473
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 307
    CTNNB1_binding; N-terminal CTNNB1 binding

  3. XM_044240527.1 → XP_044096462.1  transcription factor 7-like 2 isoform X5

    Conserved Domains (2) summary
    cd01388
    Location:406 → 473
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 307
    CTNNB1_binding; N-terminal CTNNB1 binding

  4. XM_044240526.1 → XP_044096461.1  transcription factor 7-like 2 isoform X4

    Conserved Domains (2) summary
    cd01388
    Location:401 → 468
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 307
    CTNNB1_binding; N-terminal CTNNB1 binding

  5. XM_044240525.1 → XP_044096460.1  transcription factor 7-like 2 isoform X3

    Conserved Domains (2) summary
    cd01388
    Location:402 → 469
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 307
    CTNNB1_binding; N-terminal CTNNB1 binding

  6. XM_044240524.1 → XP_044096459.1  transcription factor 7-like 2 isoform X2

    Conserved Domains (2) summary
    cd01388
    Location:405 → 472
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 306
    CTNNB1_binding; N-terminal CTNNB1 binding

  7. XM_044240529.1 → XP_044096464.1  transcription factor 7-like 2 isoform X7

    Conserved Domains (2) summary
    cd01388
    Location:383 → 450
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 284
    CTNNB1_binding; N-terminal CTNNB1 binding

  8. XM_044240530.1 → XP_044096465.1  transcription factor 7-like 2 isoform X8

    UniProtKB/TrEMBL
    A0A8C7AIG3
    Conserved Domains (1) summary
    cd01388
    Location:374 → 441
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...

  9. XM_044240548.1 → XP_044096483.1  transcription factor 7-like 2 isoform X24

    Conserved Domains (2) summary
    cd01388
    Location:406 → 473
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 307
    CTNNB1_binding; N-terminal CTNNB1 binding

  10. XM_044240549.1 → XP_044096484.1  transcription factor 7-like 2 isoform X25

    Conserved Domains (2) summary
    cd01388
    Location:405 → 472
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 306
    CTNNB1_binding; N-terminal CTNNB1 binding

  11. XM_044240544.1 → XP_044096479.1  transcription factor 7-like 2 isoform X21

    Conserved Domains (2) summary
    cd01388
    Location:406 → 473
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 307
    CTNNB1_binding; N-terminal CTNNB1 binding

  12. XM_044240550.1 → XP_044096485.1  transcription factor 7-like 2 isoform X26

    Conserved Domains (2) summary
    cd01388
    Location:406 → 473
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 307
    CTNNB1_binding; N-terminal CTNNB1 binding

  13. XM_044240532.1 → XP_044096467.1  transcription factor 7-like 2 isoform X9

    Conserved Domains (2) summary
    cd01388
    Location:358 → 425
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 259
    CTNNB1_binding; N-terminal CTNNB1 binding

  14. XM_044240535.1 → XP_044096470.1  transcription factor 7-like 2 isoform X12

    Conserved Domains (2) summary
    cd01388
    Location:358 → 425
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 259
    CTNNB1_binding; N-terminal CTNNB1 binding

  15. XM_044240534.1 → XP_044096469.1  transcription factor 7-like 2 isoform X11

    Conserved Domains (2) summary
    cd01388
    Location:353 → 420
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 259
    CTNNB1_binding; N-terminal CTNNB1 binding

  16. XM_044240536.1 → XP_044096471.1  transcription factor 7-like 2 isoform X13

    Conserved Domains (2) summary
    cd01388
    Location:353 → 420
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 259
    CTNNB1_binding; N-terminal CTNNB1 binding

  17. XM_044240533.1 → XP_044096468.1  transcription factor 7-like 2 isoform X10

    Conserved Domains (2) summary
    cd01388
    Location:354 → 421
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 259
    CTNNB1_binding; N-terminal CTNNB1 binding

  18. XM_044240538.1 → XP_044096473.1  transcription factor 7-like 2 isoform X15

    Conserved Domains (2) summary
    cd01388
    Location:349 → 416
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 259
    CTNNB1_binding; N-terminal CTNNB1 binding

  19. XM_044240537.1 → XP_044096472.1  transcription factor 7-like 2 isoform X14

    Conserved Domains (2) summary
    cd01388
    Location:335 → 402
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 236
    CTNNB1_binding; N-terminal CTNNB1 binding

  20. XM_044240541.1 → XP_044096476.1  transcription factor 7-like 2 isoform X18

    Conserved Domains (2) summary
    cd01388
    Location:335 → 402
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 236
    CTNNB1_binding; N-terminal CTNNB1 binding

  21. XM_044240539.1 → XP_044096474.1  transcription factor 7-like 2 isoform X16

    Conserved Domains (2) summary
    cd01388
    Location:330 → 397
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 236
    CTNNB1_binding; N-terminal CTNNB1 binding

  22. XM_044240543.1 → XP_044096478.1  transcription factor 7-like 2 isoform X20

    Conserved Domains (2) summary
    cd01388
    Location:330 → 397
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 236
    CTNNB1_binding; N-terminal CTNNB1 binding

  23. XM_044240542.1 → XP_044096477.1  transcription factor 7-like 2 isoform X19

    Conserved Domains (2) summary
    cd01388
    Location:330 → 397
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 236
    CTNNB1_binding; N-terminal CTNNB1 binding

  24. XM_044240540.1 → XP_044096475.1  transcription factor 7-like 2 isoform X17

    Conserved Domains (2) summary
    cd01388
    Location:326 → 393
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 236
    CTNNB1_binding; N-terminal CTNNB1 binding

  25. XM_044240551.1 → XP_044096486.1  transcription factor 7-like 2 isoform X27

    Conserved Domains (2) summary
    cd01388
    Location:406 → 473
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 307
    CTNNB1_binding; N-terminal CTNNB1 binding

  26. XM_044240555.1 → XP_044096490.1  transcription factor 7-like 2 isoform X31

    Conserved Domains (2) summary
    cd01388
    Location:358 → 425
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 259
    CTNNB1_binding; N-terminal CTNNB1 binding

  27. XM_044240553.1 → XP_044096488.1  transcription factor 7-like 2 isoform X29

    Conserved Domains (2) summary
    cd01388
    Location:353 → 420
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 259
    CTNNB1_binding; N-terminal CTNNB1 binding

  28. XM_044240552.1 → XP_044096487.1  transcription factor 7-like 2 isoform X28

    Conserved Domains (2) summary
    cd01388
    Location:377 → 444
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 283
    CTNNB1_binding; N-terminal CTNNB1 binding

  29. XM_044240554.1 → XP_044096489.1  transcription factor 7-like 2 isoform X30

    Conserved Domains (2) summary
    cd01388
    Location:335 → 402
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 236
    CTNNB1_binding; N-terminal CTNNB1 binding

  30. XM_044240556.1 → XP_044096491.1  transcription factor 7-like 2 isoform X32

    Conserved Domains (2) summary
    cd01388
    Location:353 → 420
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 259
    CTNNB1_binding; N-terminal CTNNB1 binding

  31. XM_044240557.1 → XP_044096492.1  transcription factor 7-like 2 isoform X33

    Conserved Domains (2) summary
    cd01388
    Location:349 → 416
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 259
    CTNNB1_binding; N-terminal CTNNB1 binding

  32. XM_044240558.1 → XP_044096493.1  transcription factor 7-like 2 isoform X34

    Conserved Domains (2) summary
    cd01388
    Location:330 → 397
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 236
    CTNNB1_binding; N-terminal CTNNB1 binding

  33. XM_044240560.1 → XP_044096495.1  transcription factor 7-like 2 isoform X36

    Conserved Domains (2) summary
    cd01388
    Location:330 → 397
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 236
    CTNNB1_binding; N-terminal CTNNB1 binding

  34. XM_044240559.1 → XP_044096494.1  transcription factor 7-like 2 isoform X35

    Conserved Domains (2) summary
    cd01388
    Location:326 → 393
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 236
    CTNNB1_binding; N-terminal CTNNB1 binding

  35. XM_044240561.1 → XP_044096496.1  transcription factor 7-like 2 isoform X37

    Conserved Domains (2) summary
    cd01388
    Location:326 → 393
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 236
    CTNNB1_binding; N-terminal CTNNB1 binding

  36. XM_044240545.1 → XP_044096480.1  transcription factor 7-like 2 isoform X22

    UniProtKB/TrEMBL
    A0A8C7AIG3
    Conserved Domains (2) summary
    cd01388
    Location:274 → 341
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:101 → 175
    CTNNB1_binding; N-terminal CTNNB1 binding

  37. XM_044240546.1 → XP_044096481.1  transcription factor 7-like 2 isoform X23

    UniProtKB/TrEMBL
    A0A8C7AIG3
    Conserved Domains (1) summary
    cd01388
    Location:271 → 338
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
Nucleotide Protein
Heading Accession and Version

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