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Cd24a CD24a antigen [ Mus musculus (house mouse) ]

Gene ID: 12484, updated on 6-May-2021

Summary

Official Symbol
Cd24aprovided by MGI
Official Full Name
CD24a antigenprovided by MGI
Primary source
MGI:MGI:88323
See related
Ensembl:ENSMUSG00000047139
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
H; HSA; Cd24; Ly-5; nect; Ly-52; nectadrin
Expression
Broad expression in liver E14.5 (RPKM 694.7), liver E14 (RPKM 640.9) and 20 other tissues See more
Orthologs
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Genomic context

See Cd24a in Genome Data Viewer
Location:
10 B2; 10 23.01 cM
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (43454433..43460261)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (43579169..43584265)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (43298975..43304071)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene presequence translocase-asssociated motor 16 homolog pseudogene Neighboring gene mitochondrial transcription rescue factor 1 Neighboring gene RIKEN cDNA F930017D23 gene Neighboring gene predicted gene, 51800 Neighboring gene ribosomal protein L26, pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables Hsp70 protein binding IDA
Inferred from Direct Assay
more info
PubMed 
enables Hsp90 protein binding IDA
Inferred from Direct Assay
more info
PubMed 
enables carbohydrate binding IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein kinase binding ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables protein tyrosine kinase activator activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Process Evidence Code Pubs
involved_in T cell costimulation ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
acts_upstream_of_or_within apoptotic mitochondrial changes IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within apoptotic nuclear changes IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within apoptotic signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cell activation ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 
involved_in cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within cell surface receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
involved_in chemokine receptor transport out of membrane raft IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cholesterol homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within homotypic cell-cell adhesion IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within immune system process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within innate immune response IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within leukocyte cell-cell adhesion IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within leukocyte migration involved in inflammatory response IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within negative regulation of B cell proliferation IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within negative regulation of T cell homeostatic proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within negative regulation of erythrocyte aggregation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within negative regulation of erythrocyte clearance IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of inflammatory response to wounding IPI
Inferred from Physical Interaction
more info
PubMed 
involved_in negative regulation of interleukin-6 production IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of monocyte chemotactic protein-1 production IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within negative regulation of neuroblast proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within negative regulation of neurogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within negative regulation of neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of transforming growth factor beta3 production ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in negative regulation of tumor necrosis factor production IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within neuromuscular synaptic transmission IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within neuromuscular synaptic transmission IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within neuron projection development IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within neuron projection development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within positive regulation of B cell apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of MAP kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
acts_upstream_of_or_within positive regulation of T cell homeostatic proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within positive regulation of T cell mediated immune response to tumor cell IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of activated T cell proliferation ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
acts_upstream_of_or_within positive regulation of alpha-beta T cell proliferation IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within positive regulation of alpha-beta T cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within positive regulation of calcium-mediated signaling IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within positive regulation of cell adhesion mediated by integrin IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within positive regulation of cell adhesion mediated by integrin IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within positive regulation of cell-cell adhesion IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within positive regulation of cell-cell adhesion mediated by integrin IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of cytosolic calcium ion concentration ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
acts_upstream_of_or_within positive regulation of inflammatory response to antigenic stimulus IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of inflammatory response to wounding IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within positive regulation of integrin activation IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within positive regulation of integrin activation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within positive regulation of neuron projection development IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within positive regulation of neuron projection development IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within positive regulation of peptidyl-tyrosine phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within pre-B cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within regulation of B cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of MAPK cascade ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
acts_upstream_of_or_within regulation of cell-cell adhesion IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within regulation of cell-cell adhesion mediated by integrin IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of cytokine-mediated signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of phosphorylation ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in respiratory burst ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in response to estrogen ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in response to hypoxia ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in response to molecule of bacterial origin IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within synaptic vesicle endocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in anchored component of external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in anchored component of external side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in anchored component of external side of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in anchored component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in cell surface IDA
Inferred from Direct Assay
more info
PubMed 
located_in ciliary membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in external side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in external side of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
located_in membrane raft IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane raft ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
located_in microvillus membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
signal transducer CD24
Names
M1/69-J11D heat stable antigen
R13-Ag
X62 heat stable antigen
cluster of differentiation 24
heat stable antigen
lymphocyte antigen 52

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009846.2NP_033976.1  signal transducer CD24 precursor

    See identical proteins and their annotated locations for NP_033976.1

    Status: VALIDATED

    Source sequence(s)
    AA154829, AK014279, AK133869
    Consensus CDS
    CCDS23821.1
    UniProtKB/Swiss-Prot
    P24807
    UniProtKB/TrEMBL
    Q3THW4, Q8CEU3
    Related
    ENSMUSP00000057983.9, ENSMUST00000058714.10
    Conserved Domains (1) summary
    pfam14984
    Location:2663
    CD24; CD24 protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    43454433..43460261
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036155569.1XP_036011462.1  signal transducer CD24 isoform X1

    Conserved Domains (1) summary
    pfam14984
    Location:2663
    CD24; CD24 protein
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