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LOC127407832 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:167317623-167318303 [ Homo sapiens (human) ]

Gene ID: 127407832, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127407832
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:167317623-167318303
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127407832 in Genome Data Viewer
Location:
chromosome: 6
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (166904135..166904815)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (168286890..168287570)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene ribosomal protein S6 kinase A2 Neighboring gene uncharacterized LOC124901459 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:167250099-167250620 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25439 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:167266611-167267589 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17782 Neighboring gene MPRA-validated peak6317 silencer Neighboring gene uncharacterized LOC124901461 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:167315271-167315770 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:167316941-167317622 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25440 Neighboring gene RPS6KA2 antisense RNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:167354383-167354883 Neighboring gene protein GVQW1-like Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:167363029-167363714 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25441 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:167364403-167365088 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17784 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17785 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17786 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25443 Neighboring gene CRISPRi-validated cis-regulatory element chr6.5886 Neighboring gene ribonuclease T2 Neighboring gene uncharacterized LOC105378120

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_109802.1 

    Range
    101..781
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    166904135..166904815
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    168286890..168287570
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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