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LOC127460225 H3K4me1 hESC enhancer GRCh37_chr8:122651637-122652137 [ Homo sapiens (human) ]

Gene ID: 127460225, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127460225
Gene description
H3K4me1 hESC enhancer GRCh37_chr8:122651637-122652137
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127460225 in Genome Data Viewer
Location:
chromosome: 8
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (121639397..121639897)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (122769632..122770132)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:122169222-122169753 Neighboring gene uncharacterized LOC105375731 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr8:122198893-122199426 Neighboring gene ReSE screen-validated silencer GRCh37_chr8:122281660-122281859 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:122346168-122346752 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:122346753-122347337 Neighboring gene Sharpr-MPRA regulatory region 1392 Neighboring gene ribosomal protein L35a pseudogene 19 Neighboring gene Sharpr-MPRA regulatory region 7296 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:122651136-122651636 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr8:122654339-122654962 Neighboring gene HAS2 antisense RNA 1 Neighboring gene long intergenic non-protein coding RNA 2855 Neighboring gene hyaluronan synthase 2 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr8:122835396-122836122 Neighboring gene NANOG hESC enhancer GRCh37_chr8:122856182-122856696 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:122938752-122939252 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:122939253-122939753 Neighboring gene mitochondrial ribosomal protein S36 pseudogene 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_114994.1 

    Range
    101..601
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    121639397..121639897
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    122769632..122770132
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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