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LOC127817303 OCT4-NANOG hESC enhancer GRCh37_chr10:14561637-14562152 [ Homo sapiens (human) ]

Gene ID: 127817303, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127817303
Gene description
OCT4-NANOG hESC enhancer GRCh37_chr10:14561637-14562152
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the OCT4 and NANOG transcription factors. [provided by RefSeq, Nov 2022]
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Genomic context

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Location:
chromosome: 10
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (14519638..14520153)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (14532963..14533478)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:14489756-14490256 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3070 Neighboring gene microRNA 1265 Neighboring gene uncharacterized LOC124902380 Neighboring gene MIR1265-FAM107B intergenic CAGE-defined T cell enhancer Neighboring gene uncharacterized LOC124902381 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3072 Neighboring gene family with sequence similarity 107 member B Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:14597390-14598109 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3073 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:14600759-14601636 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2160 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3074 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3075 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:14637528-14638028 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:14638029-14638529 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:14640925-14641108 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3076 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3077 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2161 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2162 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3078 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3079 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3080 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr10:14690664-14691863 Neighboring gene uncharacterized LOC105376429 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3081

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_118783.1 

    Range
    101..616
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    14519638..14520153
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    14532963..14533478
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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