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LOC127819249 NANOG-H3K4me1 hESC enhancer GRCh37_chr10:114836009-114836602 [ Homo sapiens (human) ]

Gene ID: 127819249, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127819249
Gene description
NANOG-H3K4me1 hESC enhancer GRCh37_chr10:114836009-114836602
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the NANOG transcription factor and is marked by the H3K4me1 histone modification. [provided by RefSeq, Nov 2022]
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Genomic context

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Location:
chromosome: 10
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (113076250..113076843)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (113967582..113968175)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene transcription factor 7 like 2 Neighboring gene VISTA enhancer hs1980 Neighboring gene ribosomal protein S15a pseudogene 30 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:114766090-114766810 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr10:114766811-114767531 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr10:114780025-114780562 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:114803814-114804812 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancers GRCh37_chr10:114812726-114813704 and GRCh37_chr10:114813705-114814683 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:114816611-114817110 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:114817902-114818530 Neighboring gene small nucleolar RNA, H/ACA box 87 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:114833929-114834698 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:114838433-114838934 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:114846446-114846998 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:114860474-114860640 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2836 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:114894802-114895390 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:114935734-114935902 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:114943039-114943540 Neighboring gene NANOG hESC enhancer GRCh37_chr10:115012887-115013388 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4069 Neighboring gene uncharacterized LOC105378490 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr10:115112200-115113399 Neighboring gene RNA, U7 small nuclear 165 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_120720.1 

    Range
    101..694
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    113076250..113076843
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    113967582..113968175
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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