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LOC127884557 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:75287896-75288436 [ Homo sapiens (human) ]

Gene ID: 127884557, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127884557
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:75287896-75288436
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Dec 2022]
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Genomic context

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Location:
chromosome: 16
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (75253998..75254538)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (81300747..81301287)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene chymotrypsinogen B1 Neighboring gene uncharacterized LOC100506281 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:75267182-75267807 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7711 Neighboring gene BCAR1 scaffold protein, Cas family member Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:75270483-75271324 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:75272167-75273008 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:75274691-75275532 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:75275533-75276374 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11126 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:75281985-75282648 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7712 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7713 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:75285734-75286274 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:75286815-75287355 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:75287356-75287895 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:75288976-75289516 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:75289517-75290056 Neighboring gene uncharacterized LOC105371344 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:75290057-75290597 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:75294897-75295696 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:75297293-75298090 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:75298091-75298888 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7714 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7715 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7716 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7717 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7718 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:75305973-75306511 Neighboring gene RNA, U6 small nuclear 758, pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_134335.1 

    Range
    101..641
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    75253998..75254538
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    81300747..81301287
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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