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LOC127888937 NANOG hESC enhancer GRCh37_chr18:19795797-19796446 [ Homo sapiens (human) ]

Gene ID: 127888937, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127888937
Gene description
NANOG hESC enhancer GRCh37_chr18:19795797-19796446
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer associates with the NANOG transcription factor. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127888937 in Genome Data Viewer
Location:
chromosome: 18
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 18 NC_000018.10 (22215834..22216483)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 18 NC_060942.1 (22400879..22401528)

Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr18:19747195-19747698 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:19750920-19751805 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:19751806-19752690 Neighboring gene GATA6 antisense RNA 1 (head to head) Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:19758263-19758888 Neighboring gene GATA binding protein 6 Neighboring gene RNA, U6 small nuclear 702, pseudogene Neighboring gene VISTA enhancer hs502 Neighboring gene uncharacterized LOC105372017 Neighboring gene NANOG hESC enhancer GRCh37_chr18:19798242-19798849 Neighboring gene uncharacterized LOC105372018 Neighboring gene small nucleolar RNA U13 Neighboring gene uncharacterized LOC101927548 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:19903753-19904708

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_138496.1 

    Range
    101..750
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000018.10 Reference GRCh38.p14 Primary Assembly

    Range
    22215834..22216483
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060942.1 Alternate T2T-CHM13v2.0

    Range
    22400879..22401528
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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