Y47D9A.1 Nucleotidyl transferase domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Gene symbol: Y47D9A.1
Gene description: Nucleotidyl transferase domain-containing protein
Locus tag: CELE_Y47D9A.1
See related: AllianceGenome:WB:WBGene00021628
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable nucleotidyltransferase activity. Predicted to be involved in biosynthetic process. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in alacrima, achalasia, and impaired intellectual development syndrome. Orthologous to human GMPPA (GDP-mannose pyrophosphorylase A). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See Y47D9A.1 in Genome Data Viewer

Location:: chromosome: I

Exon count:: 8

Sequence:: Chromosome: I; NC_003279.8 (4303930..4308244)

Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Y47D9A.g (e-PCR)
- UniSTS:323686

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Nucleotidyl transferase domain-containing protein

NP_491349.1

Confirmed by transcript evidence

NP_491350.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003279.8 Reference assembly

Range

4303930..4308244

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_058948.5 → NP_491349.1 Nucleotidyl transferase domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_491349.1

Status: REVIEWED

UniProtKB/TrEMBL

Q9N4V3

Conserved Domains (2) summary

cd06428
Location:5 → 244

M1P_guanylylT_A_like_N; N-terminal domain of M1P_guanylyl_A_ like proteins are likely to be a isoform of GDP-mannose pyrophosphorylase

cl00160
Location:269 → 336

LbetaH; Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes ...
NM_058949.5 → NP_491350.1 Nucleotidyl transferase domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_491350.1

Status: REVIEWED

UniProtKB/TrEMBL

Q9N4V2

Conserved Domains (2) summary

cd06428
Location:5 → 237

M1P_guanylylT_A_like_N; N-terminal domain of M1P_guanylyl_A_ like proteins are likely to be a isoform of GDP-mannose pyrophosphorylase

cl00160
Location:262 → 329

LbetaH; Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes ...