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pgal-1 putative peptidyl-alpha-hydroxyglycine alpha-amidating lyase pgal-1 [ Caenorhabditis elegans ]

Gene ID: 172108, updated on 22-May-2024

Summary

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Gene symbol
pgal-1
Gene description
putative peptidyl-alpha-hydroxyglycine alpha-amidating lyase pgal-1
Primary source
WormBase:WBGene00017671
Locus tag
CELE_F21F3.1
See related
AllianceGenome:WB:WBGene00017671
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable metal ion binding activity and peptidylamidoglycolate lyase activity. Predicted to be involved in peptide metabolic process. Predicted to be located in membrane. Predicted to be active in extracellular region. Is expressed in nervous system. Orthologous to human PAM (peptidylglycine alpha-amidating monooxygenase). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See pgal-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003279.8 (4906839..4911829)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Protein-S-isoprenylcysteine O-methyltransferase Neighboring gene Protein kinase domain-containing protein Neighboring gene DUF4149 domain-containing protein Neighboring gene Transmembrane protein 230 Neighboring gene Importin N-terminal domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables peptidylamidoglycolate lyase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in peptide metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in extracellular region IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
putative peptidyl-alpha-hydroxyglycine alpha-amidating lyase pgal-1
NP_491475.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    4906839..4911829
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059074.8 → NP_491475.2  putative peptidyl-alpha-hydroxyglycine alpha-amidating lyase pgal-1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491475.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P91268
    Conserved Domains (1) summary
    cd14958
    Location:59 → 344
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P91268.2

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