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sut-6 FHA domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 172955, updated on 25-Apr-2024

Summary

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Gene symbol
sut-6
Gene description
FHA domain-containing protein
Primary source
WormBase:WBGene00015233
Locus tag
CELE_B0511.7
See related
AllianceGenome:WB:WBGene00015233
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable mRNA binding activity and protein serine/threonine phosphatase inhibitor activity. Predicted to be involved in negative regulation of protein dephosphorylation. Predicted to be active in nuclear speck. Orthologous to human PPP1R8 (protein phosphatase 1 regulatory subunit 8). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See sut-6 in Genome Data Viewer
Location:
chromosome: I
Exon count:
5
Sequence:
Chromosome: I; NC_003279.8 (10631685..10633150, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ATP-dependent RNA helicase Neighboring gene ZP domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene Metallophosphoesterase 1 homolog

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine phosphatase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in negative regulation of protein dephosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nuclear speck IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
FHA domain-containing protein
NP_492781.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    10631685..10633150 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_060380.7 → NP_492781.2  FHA domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_492781.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    O61817
    Conserved Domains (1) summary
    cd00060
    Location:23 → 126
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
Nucleotide Protein
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