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twk-5 Potassium channel domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 174756, updated on 11-Apr-2024

Summary

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Gene symbol
twk-5
Gene description
Potassium channel domain-containing protein
Primary source
WormBase:WBGene00006660
Locus tag
CELE_B0334.2
See related
AllianceGenome:WB:WBGene00006660
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See twk-5 in Genome Data Viewer
Location:
chromosome: II
Exon count:
5
Sequence:
Chromosome: II; NC_003280.10 (11483215..11485300, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene Transthyretin-like family protein Neighboring gene FMRF-Like Peptide Neighboring gene 2-hydroxyacyl-CoA lyase 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structure and function of two-pore-domain K+ channels: contributions from genetic model organisms. Buckingham SD, et al. Trends Pharmacol Sci, 2005 Jul. PMID 15939489
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables outward rectifier potassium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables potassium channel activity IEA
Inferred from Electronic Annotation
more info
  
enables potassium ion leak channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in potassium ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in potassium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in stabilization of membrane potential IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Potassium channel domain-containing protein
NP_001021896.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    11483215..11485300 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001026725.7 → NP_001021896.1  Potassium channel domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001021896.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5FC72
    Conserved Domains (1) summary
    pfam07885
    Location:22 → 101
    Ion_trans_2; Ion channel
Nucleotide Protein
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