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idi-1 isopentenyl-diphosphate Delta-isomerase [ Caenorhabditis elegans ]

Gene ID: 176142, updated on 23-May-2024

Summary

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Gene symbol
idi-1
Gene description
isopentenyl-diphosphate Delta-isomerase
Primary source
WormBase:WBGene00019460
Locus tag
CELE_K06H7.9
See related
AllianceGenome:WB:WBGene00019460
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable isopentenyl-diphosphate delta-isomerase activity. Predicted to be involved in isopentenyl diphosphate biosynthetic process. Predicted to be active in cytoplasm. Orthologous to several human genes including IDI2 (isopentenyl-diphosphate delta isomerase 2). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See idi-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
4
Sequence:
Chromosome: III; NC_003281.10 (8091708..8093042)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene GTP exchange factor for ARFs 1 Neighboring gene tRNA endonuclease vms-1 Neighboring gene Uncharacterized protein Neighboring gene Putative serine/threonine-protein kinase K06H7.1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Isopentenyl-diphosphate isomerase is essential for viability of Caenorhabditis elegans. Yochem J, et al. Mol Genet Genomics, 2005 Apr. PMID 15765206
  2. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
  
enables isopentenyl-diphosphate delta-isomerase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables isopentenyl-diphosphate delta-isomerase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in dimethylallyl diphosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in isopentenyl diphosphate biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in isoprenoid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
isopentenyl-diphosphate Delta-isomerase
NP_001379667.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    8091708..8093042
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001392149.1 → NP_001379667.1  isopentenyl-diphosphate Delta-isomerase [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EFQ1
    Conserved Domains (1) summary
    cd02885
    Location:32 → 209
    IPP_Isomerase; Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated ...
Nucleotide Protein
Heading Accession and Version

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