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clip-1 CAP-Gly domain-containing linker protein 1 homolog [ Caenorhabditis elegans ]

Gene ID: 176307, updated on 12-Jun-2024

Summary

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Gene symbol
clip-1
Gene description
CAP-Gly domain-containing linker protein 1 homolog
Locus tag
CELE_M01A8.2
See related
AllianceGenome:WB:WBGene00010796
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables microtubule binding activity. Involved in nucleus localization and nucleus organization. Located in nuclear envelope. Is expressed in pharynx. Orthologous to human CLIP1 (CAP-Gly domain containing linker protein 1) and CLIP2 (CAP-Gly domain containing linker protein 2). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See clip-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
20
Sequence:
Chromosome: III; NC_003281.10 (9260175..9269062, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene putative RING finger protein T02C1.1 Neighboring gene RING-type E3 ubiquitin transferase Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Formin-homology and zinc finger domains protein 1 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Amphiphysin 2 Orchestrates Nucleus Positioning and Shape by Linking the Nuclear Envelope to the Actin and Microtubule Cytoskeleton. D'Alessandro M, et al. Dev Cell, 2015 Oct 26. PMID 26506308
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables microtubule binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in establishment of mitotic spindle orientation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in nuclear migration IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in nucleus localization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in nucleus organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in axon IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in kinetochore IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of microtubule associated complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nuclear envelope IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in spindle pole IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
CAP-Gly domain-containing linker protein 1 homolog
NP_001022682.1
  • Confirmed by transcript evidence
NP_001022683.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    9260175..9269062 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001027511.6 → NP_001022682.1  CAP-Gly domain-containing linker protein 1 homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022682.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34531, P34532, P34533, Q65ZC5
    Conserved Domains (1) summary
    pfam01302
    Location:22 → 85
    CAP_GLY; CAP-Gly domain

  2. NM_001027512.7 → NP_001022683.1  CAP-Gly domain-containing linker protein 1 homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022683.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34531
    Conserved Domains (1) summary
    pfam01302
    Location:22 → 85
    CAP_GLY; CAP-Gly domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P34531.4

Gene LinkOut

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