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sart-3 Nuclear RNA-binding protein sart-3 [ Caenorhabditis elegans ]

Gene ID: 178053, updated on 12-Jun-2024

Summary

Gene symbol
sart-3
Gene description
Nuclear RNA-binding protein sart-3
Locus tag
CELE_B0035.12
See related
AllianceGenome:WB:WBGene00007111
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables U4 snRNA binding activity. Predicted to be involved in eukaryotic translation initiation factor 4F complex assembly and formation of translation preinitiation complex. Located in nucleoplasm. Orthologous to human SART3 (spliceosome associated factor 3, U4/U6 recycling protein). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See sart-3 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
11
Sequence:
Chromosome: IV; NC_003282.8 (11329482..11332892, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Histone H3 Neighboring gene Kinesin motor domain-containing protein Neighboring gene RNA polymerase-associated protein LEO1 Neighboring gene Transcription termination factor 2 Neighboring gene Histone H3

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables U4 snRNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables rRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in RNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in RNA splicing IEA
Inferred from Electronic Annotation
more info
 
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Nuclear RNA-binding protein sart-3
NP_502136.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    11329482..11332892 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_069735.8NP_502136.1  Nuclear RNA-binding protein sart-3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_502136.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q17430
    Conserved Domains (3) summary
    COG0457
    Location:209494
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    pfam05391
    Location:818835
    Lsm_interact; Lsm interaction motif
    cl17169
    Location:594664
    RRM_SF; RNA recognition motif (RRM) superfamily