U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ent-1 Equilibrative nucleoside transporter 3 [ Caenorhabditis elegans ]

Gene ID: 178097, updated on 12-Jun-2024

Summary

Go to the top of the page Help
Gene symbol
ent-1
Gene description
Equilibrative nucleoside transporter 3
Locus tag
CELE_ZK809.4
See related
AllianceGenome:WB:WBGene00001320
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable nucleoside transmembrane transporter activity. Predicted to be involved in nucleoside transmembrane transport. Located in plasma membrane. Is expressed in intestine; isthmus; metacorpus; procorpus; and terminal bulb. Human ortholog(s) of this gene implicated in histiocytosis-lymphadenopathy plus syndrome. Orthologous to human SLC29A1 (solute carrier family 29 member 1 (Augustine blood group)); SLC29A2 (solute carrier family 29 member 2); and SLC29A3 (solute carrier family 29 member 3). [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See ent-1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
6
Sequence:
Chromosome: IV; NC_003282.8 (11653417..11655470, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Tafazzin family protein Neighboring gene ncRNA Neighboring gene NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Cilia- and flagella-associated protein 157

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Functional redundancy of two nucleoside transporters of the ENT family (CeENT1, CeENT2) required for development of Caenorhabditis elegans. Appleford PJ, et al. Mol Membr Biol, 2004 Jul-Aug. PMID 15371014
  2. Identification and mutational analysis of amino acid residues involved in dipyridamole interactions with human and Caenorhabditis elegans equilibrative nucleoside transporters. Visser F, et al. J Biol Chem, 2005 Mar 25. PMID 15649894
  3. Oxidative stress and longevity in Caenorhabditis elegans as mediated by SKN-1. Park SK, et al. Aging Cell, 2009 Jun. PMID 19627265, Free PMC Article
  4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables nucleoside transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleoside transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in nucleoside transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in nucleoside transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
Equilibrative nucleoside transporter 3
NP_001255573.1
  • Confirmed by transcript evidence
NP_001255574.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    11653417..11655470 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001268644.2 → NP_001255573.1  Equilibrative nucleoside transporter 3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255573.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EDJ3
    Conserved Domains (1) summary
    cl15430
    Location:151 → 440
    Nucleoside_tran; Nucleoside transporter

  2. NM_001268645.3 → NP_001255574.1  Equilibrative nucleoside transporter 3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255574.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F5GU99
    Conserved Domains (1) summary
    cl15430
    Location:1 → 124
    Nucleoside_tran; Nucleoside transporter
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools