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calf-1 CAlcium channel Localization Factor [ Caenorhabditis elegans ]

Gene ID: 180342, updated on 12-Jun-2024

Summary

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Gene symbol
calf-1
Gene description
CAlcium channel Localization Factor
Locus tag
CELE_B0250.2
See related
AllianceGenome:WB:WBGene00007119
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in several processes, including determination of left/right asymmetry in nervous system; protein exit from endoplasmic reticulum; and protein localization to synapse. Located in endoplasmic reticulum membrane. Is expressed in neurons. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See calf-1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
5
Sequence:
Chromosome: V; NC_003283.11 (20476747..20479089, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene DUF4258 domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Large ribosomal subunit protein uL2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Calcium: an insignificant thing. Frøkjaer-Jensen C, et al. Nat Neurosci, 2009 Oct. PMID 19783977, Free PMC Article
  2. Excitatory motor neurons are local oscillators for backward locomotion. Gao S, et al. Elife, 2018 Jan 23. PMID 29360035, Free PMC Article
  3. Presynaptic CaV2 calcium channel traffic requires CALF-1 and the alpha(2)delta subunit UNC-36. Saheki Y, et al. Nat Neurosci, 2009 Oct. PMID 19718034, Free PMC Article
  4. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in determination of left/right asymmetry in nervous system IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of locomotion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein exit from endoplasmic reticulum IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein localization to synapse IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
CAlcium channel Localization Factor
NP_507939.1
  • Product from WormBase gene class calf;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    20476747..20479089 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_075538.8 → NP_507939.1  CAlcium channel Localization Factor [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_507939.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9XVF6
Nucleotide Protein
Heading Accession and Version

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