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sfxn-1.4 Sideroflexin-2;Sidoreflexin [ Caenorhabditis elegans ]

Gene ID: 183547, updated on 25-Apr-2024

Summary

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Gene symbol
sfxn-1.4
Gene description
Sideroflexin-2;Sidoreflexin
Primary source
WormBase:WBGene00008137
Locus tag
CELE_C47D12.3
See related
AllianceGenome:WB:WBGene00008137
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable serine transmembrane transporter activity. Predicted to be involved in serine import into mitochondrion. Predicted to be located in mitochondrial membrane. Predicted to be integral component of membrane. Predicted to be integral component of mitochondrial inner membrane. Orthologous to human SFXN1 (sideroflexin 1) and SFXN3 (sideroflexin 3). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See sfxn-1.4 in Genome Data Viewer
Location:
chromosome: II
Exon count:
5
Sequence:
Chromosome: II; NC_003280.10 (11679091..11681236, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Transcription-associated protein 1 Neighboring gene Dymeclin Neighboring gene F-box domain-containing protein Neighboring gene CUB domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables monoatomic ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in amino acid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in serine import into mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrial inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrial membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Sideroflexin-2;Sidoreflexin
NP_001254308.1
  • Confirmed by transcript evidence
NP_001379510.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    11679091..11681236 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001267379.4 → NP_001254308.1  Sidoreflexin [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001254308.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q18666
    Conserved Domains (1) summary
    TIGR00798
    Location:13 → 326
    mtc; tricarboxylate carrier

  2. NM_001393201.1 → NP_001379510.1  Sideroflexin-2 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    D3KFU4
    Conserved Domains (1) summary
    cl04275
    Location:1 → 156
    Mtc; Tricarboxylate carrier
Nucleotide Protein
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