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famh-161 Protein fam-161 [ Caenorhabditis elegans ]

Gene ID: 189695, updated on 12-Jun-2024

Summary

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Gene symbol
famh-161
Gene description
Protein fam-161
Locus tag
CELE_Y38H6C.14
See related
AllianceGenome:WB:WBGene00012626
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in cilium organization. Located in axoneme; ciliary base; and ciliary transition zone. Is expressed in ciliated neurons. Human ortholog(s) of this gene implicated in retinitis pigmentosa 28. Orthologous to several human genes including FAM161B (FAM161 centrosomal protein B). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See famh-161 in Genome Data Viewer
Location:
chromosome: V
Exon count:
9
Sequence:
Chromosome: V; NC_003283.11 (20529696..20534172, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Transposase Neighboring gene F-box domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene EXPERA domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Whole-Organism Developmental Expression Profiling Identifies RAB-28 as a Novel Ciliary GTPase Associated with the BBSome and Intraflagellar Transport. Jensen VL, et al. PLoS Genet, 2016 Dec. PMID 27930654, Free PMC Article
  2. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
  3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in cilium organization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in axoneme IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in ciliary base IDA
Inferred from Direct Assay
more info
 PubMed 
located_in ciliary transition zone IDA
Inferred from Direct Assay
more info
 PubMed 
colocalizes_with cilium IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cilium IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Protein fam-161
NP_507957.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    20529696..20534172 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_075556.6 → NP_507957.1  Protein fam-161 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_507957.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9XX47
    Conserved Domains (1) summary
    pfam10595
    Location:357 → 628
    UPF0564; Uncharacterized protein family UPF0564
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9XX47.1

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