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ins-2 putative insulin-like peptide beta-type 2 [ Caenorhabditis elegans ]

Gene ID: 191217, updated on 12-Jun-2024

Summary

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Gene symbol
ins-2
Gene description
putative insulin-like peptide beta-type 2
Locus tag
CELE_ZK75.2
See related
AllianceGenome:WB:WBGene00002085
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable hormone activity. Involved in negative regulation of dauer entry. Predicted to be located in extracellular region. Is expressed in amphid sensillum; ciliated neurons; head muscle; intestine; and nerve ring. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See ins-2 in Genome Data Viewer
Location:
chromosome: II
Exon count:
2
Sequence:
Chromosome: II; NC_003280.10 (5988524..5989426)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene ncRNA Neighboring gene putative insulin-like peptide beta-type 3 Neighboring gene putative insulin-like peptide beta-type 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A Caenorhabditis elegans developmental decision requires insulin signaling-mediated neuron-intestine communication. Hung WL, et al. Development, 2014 Apr. PMID 24671950, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables hormone activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in negative regulation of dauer entry IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
putative insulin-like peptide beta-type 2
NP_495194.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    5988524..5989426
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_062793.2 → NP_495194.1  putative insulin-like peptide beta-type 2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_495194.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q09627
    Conserved Domains (1) summary
    pfam03488
    Location:55 → 101
    Ins_beta; Nematode insulin-related peptide beta type
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q09627.1

Gene LinkOut

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