apoa1a - apolipoprotein A-Ia
Predicted to enable several functions, including cholesterol binding activity; cholesterol transfer activity; and high-density lipoprotein particle binding activity. Predicted to be involved in several processes, including lipid homeostasis; lipid transport; and plasma lipoprotein particle organization. Predicted to act upstream of or within cholesterol metabolic process and cholesterol transport. Located in extracellular region. Is expressed in intestine; liver; ovary; ventral telencephalon; and yolk syncytial layer. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); familial visceral amyloidosis; hypolipoproteinemia (multiple); non-alcoholic steatohepatitis; and systemic lupus erythematosus. Orthologous to human APOA1 (apolipoprotein A1). [provided by Alliance of Genome Resources, Apr 2022]
NCBI Orthologs
How was this calculated?genes for:
Protein alignment
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Species | Gene | Architecture | aa |
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