U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Kiaa1614 KIAA1614 homolog [ Rattus norvegicus (Norway rat) ]

Gene ID: 305101, updated on 13-Apr-2024

Summary

Official Symbol
Kiaa1614provided by RGD
Official Full Name
KIAA1614 homologprovided by RGD
Primary source
RGD:1304622
See related
Ensembl:ENSRNOG00000000040 AllianceGenome:RGD:1304622
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1304622
Summary
Predicted to enable protein kinase C binding activity. Predicted to be involved in centrosome cycle; establishment or maintenance of cell polarity; and regulation of cellular localization. Predicted to be active in apical plasma membrane; cell cortex; and nucleus. Orthologous to human KIAA1614 (KIAA1614). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 48.5), Heart (RPKM 23.4) and 8 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Kiaa1614 in Genome Data Viewer
Location:
13q21
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (69939228..69977703, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (67388916..67427392, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (72860313..72900020, complement)

Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene large ribosomal subunit protein uL29-like Neighboring gene syntaxin 6 Neighboring gene xenotropic and polytropic retrovirus receptor 1 Neighboring gene uncharacterized LOC102553685

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in centrosome cycle IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in establishment or maintenance of cell polarity IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of cellular localization IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in apical plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in cell cortex IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
uncharacterized protein KIAA1614 homolog

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001427644.1NP_001414573.1  uncharacterized protein KIAA1614 homolog

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000013
    UniProtKB/TrEMBL
    A0A1W2Q6M3

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086031.1 Reference GRCr8

    Range
    69939228..69977703 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006250087.5XP_006250149.1  uncharacterized protein KIAA1614 homolog isoform X2

    See identical proteins and their annotated locations for XP_006250149.1

    Conserved Domains (2) summary
    cd00992
    Location:10771158
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15737
    Location:313436
    DUF4685; Domain of unknown function (DUF4685)
  2. XM_006250088.5XP_006250150.1  uncharacterized protein KIAA1614 homolog isoform X3

    Conserved Domains (2) summary
    cd00992
    Location:10611142
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15737
    Location:343420
    DUF4685; Domain of unknown function (DUF4685)
  3. XM_017598985.3XP_017454474.1  uncharacterized protein KIAA1614 homolog isoform X1

  4. XM_039091362.1XP_038947290.1  uncharacterized protein KIAA1614 homolog isoform X5

    Conserved Domains (2) summary
    cd00992
    Location:739820
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15737
    Location:198
    DUF4685; Domain of unknown function (DUF4685)
  5. XM_039091363.1XP_038947291.1  uncharacterized protein KIAA1614 homolog isoform X6

    Conserved Domains (2) summary
    cd00992
    Location:674755
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15737
    Location:133
    DUF4685; Domain of unknown function (DUF4685)
  6. XM_017598990.3XP_017454479.1  uncharacterized protein KIAA1614 homolog isoform X5

    Conserved Domains (2) summary
    cd00992
    Location:739820
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15737
    Location:198
    DUF4685; Domain of unknown function (DUF4685)
  7. XM_006250090.5XP_006250152.1  uncharacterized protein KIAA1614 homolog isoform X4

    UniProtKB/TrEMBL
    A6ICY7
    Conserved Domains (1) summary
    pfam15737
    Location:345468
    DUF4685; Domain of unknown function (DUF4685)