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Sfi1 SFI1 centrin binding protein [ Rattus norvegicus (Norway rat) ]

Gene ID: 305467, updated on 3-Apr-2024

Summary

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Official Symbol
Sfi1provided by RGD
Official Full Name
SFI1 centrin binding proteinprovided by RGD
Primary source
RGD:1560636
See related
Ensembl:ENSRNOG00000018412 AllianceGenome:RGD:1560636
Gene type
protein coding
RefSeq status
INFERRED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1560636
Summary
Predicted to enable phosphatase binding activity. Orthologous to human SFI1 (SFI1 centrin binding protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 53.7), Kidney (RPKM 53.5) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
14q21
Exon count:
35
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (82215423..82272811, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (77990965..78048352, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (83341900..83412733, complement)

Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene ATP synthase subunit epsilon, mitochondrial-like Neighboring gene proline rich 14-like Neighboring gene phosphatidylserine decarboxylase Neighboring gene uncharacterized LOC134481863 Neighboring gene eukaryotic translation initiation factor 4E nuclear import factor 1 Neighboring gene small nuclear ribonucleoprotein polypeptide G, pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Docking motif-guided mapping of the interactome of protein phosphatase-1. Hendrickx A, et al. Chem Biol, 2009 Apr 24. PMID 19389623
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables phosphatase binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatase binding ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
protein SFI1 homolog
Names
Sfi1 homolog, spindle assembly associated

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001191682.1 → NP_001178611.1  protein SFI1 homolog

    See identical proteins and their annotated locations for NP_001178611.1

    Status: INFERRED

    Source sequence(s)
    JAXUCZ010000014
    UniProtKB/TrEMBL
    A0A8I5ZPC0, D3ZTG6
    Related
    ENSRNOP00000037698.5, ENSRNOT00000036848.7
    Conserved Domains (1) summary
    pfam08457
    Location:214 → 805
    Sfi1; Sfi1 spindle body protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086032.1 Reference GRCr8

    Range
    82215423..82272811 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039091999.2 → XP_038947927.1  protein SFI1 homolog isoform X2

    UniProtKB/TrEMBL
    A0A8I5ZPC0
    Conserved Domains (2) summary
    TIGR02169
    Location:1109 → 1202
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam08457
    Location:323 → 805
    Sfi1; Sfi1 spindle body protein

  2. XM_063273185.1 → XP_063129255.1  protein SFI1 homolog isoform X1

    UniProtKB/TrEMBL
    D3ZTG6

  3. XM_039092000.2 → XP_038947928.1  protein SFI1 homolog isoform X3

    UniProtKB/TrEMBL
    A0A8I5ZPC0
    Conserved Domains (1) summary
    pfam08457
    Location:323 → 805
    Sfi1; Sfi1 spindle body protein

  4. XM_039092001.2 → XP_038947929.1  protein SFI1 homolog isoform X4

    Conserved Domains (1) summary
    pfam08457
    Location:323 → 809
    Sfi1; Sfi1 spindle body protein

RNA

  1. XR_001841023.3 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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