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gdf7 growth differentiation factor 7 [ Danio rerio (zebrafish) ]

Gene ID: 30642, updated on 27-Mar-2024

Summary

Official Symbol
gdf7provided by ZNC
Official Full Name
growth differentiation factor 7provided by ZNC
Primary source
ZFIN:ZDB-GENE-990714-1
See related
Ensembl:ENSDARG00000042784 AllianceGenome:ZFIN:ZDB-GENE-990714-1
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
bmp12
Summary
Predicted to enable cytokine activity. Predicted to be involved in BMP signaling pathway; SMAD protein signal transduction; and positive regulation of pathway-restricted SMAD protein phosphorylation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including brain; cardiovascular system; liver; muscle; and pleuroperitoneal region. Orthologous to human GDF7 (growth differentiation factor 7). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See gdf7 in Genome Data Viewer
Location:
chromosome: 17
Exon count:
2
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (30833347..30840643, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (30817856..30822766, complement)

Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene apolipoprotein Ba Neighboring gene lipid droplet associated hydrolase Neighboring gene tripeptidyl peptidase I Neighboring gene YY1 transcription factor a

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables cytokine activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in BMP signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
growth differentiation factor 7; growth/differentiation factor 6-A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007128.7 Reference GRCz11 Primary Assembly

    Range
    30833347..30840643 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_689471.6XP_694563.2  growth/differentiation factor 6-A

    UniProtKB/TrEMBL
    A0A8N7TFB7
    Related
    ENSDARP00000118202.1, ENSDART00000139707.2
    Conserved Domains (2) summary
    smart00204
    Location:324422
    TGFB; Transforming growth factor-beta (TGF-beta) family
    pfam00688
    Location:62250
    TGFb_propeptide; TGF-beta propeptide