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Trmt9b tRNA methyltransferase 9B (putative) [ Rattus norvegicus (Norway rat) ]

Gene ID: 306504, updated on 3-Apr-2024

Summary

Symbol
Trmt9bprovided by RGD
Full Name
tRNA methyltransferase 9B (putative)provided by RGD
Primary source
RGD:1304810
See related
Ensembl:ENSRNOG00000011253 AllianceGenome:RGD:1304810
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1304810
Summary
Predicted to enable tRNA binding activity and tRNA methyltransferase activity. Predicted to be involved in tRNA wobble uridine modification. Predicted to be active in cytoplasm and nucleus. Orthologous to human TRMT9B (tRNA methyltransferase 9B (putative)). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 62.0), Adrenal (RPKM 42.5) and 8 other tissues See more
Orthologs
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Genomic context

See Trmt9b in Genome Data Viewer
Location:
16q12.2
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (62439625..62495526, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (55740551..55792198, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (59316145..59368559, complement)

Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene DLC1 Rho GTPase activating protein Neighboring gene uncharacterized LOC108348402 Neighboring gene uncharacterized LOC120097448 Neighboring gene ubiquitin-conjugating enzyme E2E 3, pseudogene 2 Neighboring gene sorcin, pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables S-adenosylmethionine-dependent methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables tRNA (5-carboxymethyluridine(34)-5-O)-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables tRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables tRNA methyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in tRNA methylation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in tRNA wobble uridine modification IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
probable tRNA methyltransferase 9B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107314.1NP_001100784.1  probable tRNA methyltransferase 9B

    See identical proteins and their annotated locations for NP_001100784.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473970
    UniProtKB/TrEMBL
    A6IVK2, A6IVK5, D3ZQW3
    Related
    ENSRNOP00000015062.3, ENSRNOT00000015062.4
    Conserved Domains (1) summary
    pfam08241
    Location:50139
    Methyltransf_11; Methyltransferase domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086034.1 Reference GRCr8

    Range
    62439625..62495526 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063275436.1XP_063131506.1  probable tRNA methyltransferase 9B isoform X3

    UniProtKB/TrEMBL
    A6IVK9
  2. XM_063275435.1XP_063131505.1  probable tRNA methyltransferase 9B isoform X2

  3. XM_006253223.5XP_006253285.1  probable tRNA methyltransferase 9B isoform X1

    See identical proteins and their annotated locations for XP_006253285.1

    UniProtKB/TrEMBL
    A6IVK2, A6IVK5, D3ZQW3
    Conserved Domains (1) summary
    pfam08241
    Location:50139
    Methyltransf_11; Methyltransferase domain
  4. XM_006253222.3XP_006253284.1  probable tRNA methyltransferase 9B isoform X1

    See identical proteins and their annotated locations for XP_006253284.1

    UniProtKB/TrEMBL
    A6IVK2, A6IVK5, D3ZQW3
    Conserved Domains (1) summary
    pfam08241
    Location:50139
    Methyltransf_11; Methyltransferase domain
  5. XM_039094541.2XP_038950469.1  probable tRNA methyltransferase 9B isoform X3

    UniProtKB/TrEMBL
    A6IVK5, A6IVK9