tpst1 tyrosylprotein sulfotransferase 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: tpst1provided by ZNC
Official Full Name: tyrosylprotein sulfotransferase 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-000210-10
See related: Ensembl:ENSDARG00000073872 AllianceGenome:ZFIN:ZDB-GENE-000210-10
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fj54g11; wu:fj54g11
Summary: Predicted to enable protein-tyrosine sulfotransferase activity. Predicted to be involved in peptidyl-tyrosine sulfation. Predicted to be integral component of Golgi membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including alar plate midbrain region; immature eye; integument; nervous system; and periderm. Orthologous to human TPST1 (tyrosylprotein sulfotransferase 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 15

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	15	NC_007126.7 (20652653..20731606, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	15	NC_007126.6 (20716921..20795876, complement)

Chromosome 15 - NC_007126.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fc42c01.y1 (e-PCR)
- UniSTS:193807

fi27g02.x1 (e-PCR)
- UniSTS:197165

fj54g11.x1 (e-PCR)
- UniSTS:199556

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables protein-tyrosine sulfotransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein-tyrosine sulfotransferase activity	IEA Inferred from Electronic Annotation more info
enables protein-tyrosine sulfotransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in peptidyl-tyrosine sulfation	IBA Inferred from Biological aspect of Ancestor more info
involved_in post-translational protein modification	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in Golgi apparatus	IBA Inferred from Biological aspect of Ancestor more info
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
located_in Golgi membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: protein-tyrosine sulfotransferase 1

Names: TPST-1

NP_571478.1

EC 2.8.2.20

XP_005157559.1

EC 2.8.2.20

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_131403.1 → NP_571478.1 protein-tyrosine sulfotransferase 1

See identical proteins and their annotated locations for NP_571478.1

Status: PROVISIONAL

Source sequence(s)

BC056786

UniProtKB/Swiss-Prot

Q804S9, Q9PTE6

Related

ENSDARP00000101352.1, ENSDART00000114464.4

Conserved Domains (1) summary

pfam13469
Location:66 → 253

Sulfotransfer_3; Sulfotransferase family

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007126.7 Reference GRCz11 Primary Assembly

Range

20652653..20731606 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005157502.4 → XP_005157559.1 protein-tyrosine sulfotransferase 1 isoform X1

UniProtKB/TrEMBL

A0A0R4IQR2, A0A8M2B4A9

Related

ENSDARP00000138186.1, ENSDART00000170616.3

Conserved Domains (1) summary

pfam13469
Location:66 → 253

Sulfotransfer_3; Sulfotransferase family