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usp - ultraspiracle

Enables several functions, including nuclear receptor activity; protein heterodimerization activity; and transcription cis-regulatory region binding activity. Contributes to DNA-binding transcription activator activity, RNA polymerase II-specific and ecdysone binding activity. Involved in several processes, including border follicle cell migration; instar larval or pupal development; and nervous system development. Located in dendrite and nucleus. Part of activator ecdysone receptor complex. Is expressed in several structures, including central nervous system; gut; imaginal disc; reproductive system; and ring gland. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma and pancreatic cancer. Orthologous to several human genes including RXRA (retinoid X receptor alpha) and RXRG (retinoid X receptor gamma). [provided by Alliance of Genome Resources, Apr 2022]

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Species Gene Architecture aa