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Atad2 ATPase family, AAA domain containing 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 314993, updated on 30-Sep-2021

Summary

Official Symbol
Atad2provided by RGD
Official Full Name
ATPase family, AAA domain containing 2provided by RGD
Primary source
RGD:1304849
See related
EnsemblRapid:ENSRNOG00000025604
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Thymus (RPKM 206.0), Spleen (RPKM 178.4) and 9 other tissues See more
Orthologs
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Genomic context

See Atad2 in Genome Data Viewer
Location:
7q33
Exon count:
30
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (89634123..89676738, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (97984754..98027379)

Chromosome 7 - NC_051342.1Genomic Context describing neighboring genes Neighboring gene zinc fingers and homeoboxes 1 Neighboring gene similar to ribosomal protein S10 Neighboring gene U7 small nuclear RNA Neighboring gene small nucleolar RNA SNORA11 Neighboring gene N-terminal glutamine amidase 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables ATP hydrolysis activity ISO
Inferred from Sequence Orthology
more info
 
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables histone binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in chromatin organization IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
ATPase family AAA domain-containing protein 2
NP_001128351.1
XP_038935135.1
XP_038935137.1
XP_038935138.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001134879.1NP_001128351.1  ATPase family AAA domain-containing protein 2

    See identical proteins and their annotated locations for NP_001128351.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473950
    Related
    ENSRNOP00000079642.1, ENSRNOT00000112469.1
    Conserved Domains (3) summary
    cd05528
    Location:9721082
    Bromo_AAA; Bromodomain; sub-family co-occurring with AAA domains. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine. The structure(2DKW) in this ...
    smart00382
    Location:444585
    AAA; ATPases associated with a variety of cellular activities
    pfam00004
    Location:449583
    AAA; ATPase family associated with various cellular activities (AAA)

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051342.1 Reference mRatBN7.2 Primary Assembly

    Range
    89634123..89676738 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039079207.1XP_038935135.1  ATPase family AAA domain-containing protein 2 isoform X1

    Conserved Domains (3) summary
    cd05528
    Location:9191029
    Bromo_AAA; Bromodomain; sub-family co-occurring with AAA domains. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine. The structure(2DKW) in this ...
    COG0464
    Location:377866
    SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]
    cd19517
    Location:359528
    RecA-like_Yta7-like; ATPase domain of Saccharomyces cerevisiae Yta7 and similar ATPase domains
  2. XM_039079209.1XP_038935137.1  ATPase family AAA domain-containing protein 2 isoform X2

    Related
    ENSRNOP00000081791.1, ENSRNOT00000117872.1
    Conserved Domains (3) summary
    cd05528
    Location:643753
    Bromo_AAA; Bromodomain; sub-family co-occurring with AAA domains. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine. The structure(2DKW) in this ...
    COG0464
    Location:101590
    SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]
    cd19517
    Location:83252
    RecA-like_Yta7-like; ATPase domain of Saccharomyces cerevisiae Yta7 and similar ATPase domains
  3. XM_039079210.1XP_038935138.1  ATPase family AAA domain-containing protein 2 isoform X3

    Conserved Domains (3) summary
    cd05528
    Location:547657
    Bromo_AAA; Bromodomain; sub-family co-occurring with AAA domains. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine. The structure(2DKW) in this ...
    COG0464
    Location:5494
    SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]
    cl38936
    Location:1156
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
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