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anapc5 anaphase promoting complex subunit 5 [ Danio rerio (zebrafish) ]

Gene ID: 322854, updated on 19-Jun-2024

Summary

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Official Symbol
anapc5provided by ZNC
Official Full Name
anaphase promoting complex subunit 5provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-1574
See related
Ensembl:ENSDARG00000008461 AllianceGenome:ZFIN:ZDB-GENE-030131-1574
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:55800; wu:fb75a09
Summary
Predicted to be involved in anaphase-promoting complex-dependent catabolic process; positive regulation of mitotic metaphase/anaphase transition; and protein K11-linked ubiquitination. Predicted to act upstream of or within cell division. Predicted to be part of anaphase-promoting complex. Orthologous to human ANAPC5 (anaphase promoting complex subunit 5). [provided by Alliance of Genome Resources, Apr 2022]
Annotation information
Annotation category: suggests misassembly
Orthologs
human mouse all
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Genomic context

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See anapc5 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
17
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (40186511..40205078, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (40152737..40171304, complement)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 75Ba Neighboring gene glutathione peroxidase 8 (putative) Neighboring gene ring finger protein 34a Neighboring gene lysine (K)-specific demethylase 2Ba

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Transcriptional and histological alterations in gonad of adult zebrafish after exposure to the synthetic progestin norgestrel. Shi WJ, et al. Environ Toxicol Chem, 2017 Dec. PMID 28631837
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in anaphase-promoting complex-dependent catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of mitotic metaphase/anaphase transition IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein K11-linked ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of anaphase-promoting complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of anaphase-promoting complex IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in spindle IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
anaphase-promoting complex subunit 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199622.2 → NP_955916.2  anaphase-promoting complex subunit 5

    Status: VALIDATED

    Source sequence(s)
    CABZ01073597, CABZ01073598, EH552132
    UniProtKB/TrEMBL
    A0A8M1PFK7
    Related
    ENSDARP00000132075.1, ENSDART00000158927.3
    Conserved Domains (3) summary
    sd00016
    Location:253 → 287
    Apc5; TPR repeat [structural motif]
    pfam12862
    Location:259 → 359
    ANAPC5; Anaphase-promoting complex subunit 5
    cd16270
    Location:32 → 161
    Apc5_N; N-terminal domain of the anaphase-promoting complex subunit Apc5 (or Anapc5)

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    40186511..40205078 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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