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cops4 COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) [ Danio rerio (zebrafish) ]

Gene ID: 325592, updated on 11-Apr-2024

Summary

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Official Symbol
cops4provided by ZNC
Official Full Name
COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-4317
See related
Ensembl:ENSDARG00000043732 AllianceGenome:ZFIN:ZDB-GENE-030131-4317
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc90c08; zgc:77137; wu:fc90c08
Summary
Predicted to be located in nucleus and synaptic vesicle. Predicted to be part of COP9 signalosome. Is expressed in liver. Orthologous to human COPS4 (COP9 signalosome subunit 4). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See cops4 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
10
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (11355884..11368477)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (11397646..11410238)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene ints3 and nabp interacting protein Neighboring gene lin-54 DREAM MuvB core complex component Neighboring gene placenta associated 8, tandem duplicate 2 Neighboring gene placenta associated 8, tandem duplicate 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Loss of smarcad1a accelerates tumorigenesis of malignant peripheral nerve sheath tumors in zebrafish. Han H, et al. Genes Chromosomes Cancer, 2021 Nov. PMID 34296799, Free PMC Article
  2. Def functions as a cell autonomous factor in organogenesis of digestive organs in zebrafish. Tao T, et al. PLoS One, 2013. PMID 23593122, Free PMC Article
  3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
part_of COP9 signalosome IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of COP9 signalosome IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in synapse IEA
Inferred from Electronic Annotation
more info
  
located_in synaptic vesicle IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
COP9 signalosome complex subunit 4
Names
signalosome subunit 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205556.1 → NP_991119.1  COP9 signalosome complex subunit 4

    See identical proteins and their annotated locations for NP_991119.1

    Status: PROVISIONAL

    Source sequence(s)
    BC065617
    UniProtKB/Swiss-Prot
    Q6P0H6, Q6PHJ7
    Related
    ENSDARP00000064214.4, ENSDART00000064215.5
    Conserved Domains (2) summary
    COG5071
    Location:88 → 377
    RPN5; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]
    pfam01399
    Location:264 → 362
    PCI; PCI domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    11355884..11368477
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005155593.4 → XP_005155650.1  COP9 signalosome complex subunit 4 isoform X1

    UniProtKB/TrEMBL
    A0A2R8QL66, A0A8M2B242
    Related
    ENSDARP00000153791.1, ENSDART00000193067.1
    Conserved Domains (2) summary
    COG5071
    Location:88 → 378
    RPN5; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]
    pfam01399
    Location:264 → 363
    PCI; PCI domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6P0H6.1 GenPept UniProtKB/Swiss-Prot:Q6P0H6

Gene LinkOut

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