cul5a cullin 5a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cul5aprovided by ZNC
Official Full Name: cullin 5aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-5426
See related: Ensembl:ENSDARG00000069742 AllianceGenome:ZFIN:ZDB-GENE-030131-5426
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cul5; zgc:66185; wu:fd17d09; wu:fi20h12; xx:11fd17d09
Summary: Predicted to enable ubiquitin protein ligase binding activity and ubiquitin-protein transferase activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and protein ubiquitination. Predicted to act upstream of or within ubiquitin-dependent protein catabolic process. Predicted to be part of Cul5-RING ubiquitin ligase complex and SCF ubiquitin ligase complex. Orthologous to human CUL5 (cullin 5). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 15

Exon count:: 19

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	15	NC_007126.7 (17144968..17169935, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	15	NC_007126.6 (17208946..17233913, complement)

Chromosome 15 - NC_007126.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables protein-macromolecule adaptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables ubiquitin protein ligase binding	IBA Inferred from Biological aspect of Ancestor more info
enables ubiquitin protein ligase binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein ubiquitination	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein ubiquitination	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within ubiquitin-dependent protein catabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of Cul5-RING ubiquitin ligase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of SCF ubiquitin ligase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of cullin-RING ubiquitin ligase complex	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: cullin-5a

Names: cullin 5

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001328059.1 → NP_001314988.1 cullin-5a

Status: VALIDATED

Source sequence(s)

BX572630

UniProtKB/TrEMBL

A0A8M1P4A8, F1REN0

Related

ENSDARP00000100474.3, ENSDART00000110111.4

Conserved Domains (3) summary

smart00182
Location:443 → 586

CULLIN; Cullin

pfam00888
Location:20 → 671

Cullin; Cullin family

pfam10557
Location:713 → 772

Cullin_Nedd8; Cullin protein neddylation domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007126.7 Reference GRCz11 Primary Assembly

Range

17144968..17169935 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

NW_018394943.1 Reference GRCz11 ALT_DRER_TU_1

Range

261839..286806 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_2

Genomic

NW_018395321.1 Reference GRCz11 ALT_DRER_TU_2

Range

108347..131967 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_212706.1: Suppressed sequence

Description

NM_212706.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.