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agfg1a ArfGAP with FG repeats 1a [ Danio rerio (zebrafish) ]

Gene ID: 327597, updated on 27-Mar-2024

Summary

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Official Symbol
agfg1aprovided by ZNC
Official Full Name
ArfGAP with FG repeats 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-5808
See related
Ensembl:ENSDARG00000030020 AllianceGenome:ZFIN:ZDB-GENE-030131-5808
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
hrb; agfg1; wu:fb14f05; wu:fi19d11
Summary
Predicted to enable GTPase activator activity and metal ion binding activity. Is expressed in intermediate cell mass of mesoderm and ventral mesoderm. Orthologous to human AGFG1 (ArfGAP with FG repeats 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See agfg1a in Genome Data Viewer
Location:
chromosome: 15
Exon count:
15
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (35156413..35212809, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (35298445..35354877, complement)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene palmitoyl-protein thioesterase 2a, tandem duplicate 4 Neighboring gene serine/threonine-protein kinase pim-2-like Neighboring gene solute carrier family 19 member 3a Neighboring gene mitochondrial ribosomal protein L44 Neighboring gene mitochondrial fission factor a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  2. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in acrosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intermediate filament organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in spermatid nucleus differentiation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasmic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
arf-GAP domain and FG repeat-containing protein 1; arf-GAP domain and FG repeat-containing protein 1a
Names
ArfGAP with FG repeats 1
HIV-1 Rev binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199835.1 → NP_956129.1  arf-GAP domain and FG repeat-containing protein 1a

    See identical proteins and their annotated locations for NP_956129.1

    Status: PROVISIONAL

    Source sequence(s)
    AY423015
    UniProtKB/TrEMBL
    Q6TEN4
    Related
    ENSDARP00000043959.6, ENSDART00000043960.8
    Conserved Domains (1) summary
    smart00105
    Location:17 → 134
    ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    35156413..35212809 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021481343.1 → XP_021337018.1  arf-GAP domain and FG repeat-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M9QBV1
    Conserved Domains (2) summary
    smart00105
    Location:17 → 134
    ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
    cl26386
    Location:365 → 594
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

  2. XM_009291790.3 → XP_009290065.1  arf-GAP domain and FG repeat-containing protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A8M3AQ06
    Conserved Domains (1) summary
    smart00105
    Location:17 → 134
    ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF

  3. XM_009291789.3 → XP_009290064.1  arf-GAP domain and FG repeat-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8M3ASW7
    Conserved Domains (1) summary
    smart00105
    Location:17 → 134
    ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF

  4. XM_021481344.1 → XP_021337019.1  arf-GAP domain and FG repeat-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8M9QH37
    Conserved Domains (2) summary
    smart00105
    Location:17 → 134
    ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
    cl26386
    Location:365 → 578
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
Nucleotide Protein Strain
Heading Accession and Version

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